产品编号 A7085 | CAS号 103-90-2 | SIGMA-ALDRICH
Application：镇痛剂。
包装：1 kg in glass bottle，100, 500 g in glass bottle
| Related Categories | Building Blocks, C6 to C8, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds, |
| product line | BioXtra |
| assay | ≥99.0% |
| form | powder |
| impurities | ≤0.0005% Phosphorus (P) |
| ≤0.1% Insoluble matter | |
| ign. residue | ≤0.1% |
| mp | 168-172 °C(lit.) |
Sigma丝裂霉素 C 来源于头状链霉菌
产品编号 M0503-2mg | CAS号 50-07-7 | SIGMA
Frequently Asked Questions
Frequently Asked Questions
are available for this Product.
Application
Mitomycin C is produced by a strain of actinomyces, Streptomyces caespitosus. It contains three anticancer moieties, quinine, urethane, and aziridine groups. It is used to generate mitotically inactive feeder cells in cell culture systems, such as the mitotically inactive fibroblasts used in embryonic stem cell systems.
Biochem/physiol Actions
DNA 合成、细胞核分裂和癌细胞的抑制剂。对革兰氏阳性菌、
Caution
This vial contains 2 mg Mitomycin C and 48 mg NaCl. Stock solutions should be filter sterilized and stored at 2-8°C in the dark. Solutions at pH 6-9 can be stored at 0-5°C for up to a week, but if a precipitate forms, a fresh solution should be prepared – the precipitated solution has been proven toxic to cells.
Preparation Note
Mitomycin C is soluble in water at .5 mg/mL, with a pH of 6.0-7.5. It undergoes rapid degradation in acidic solutions with pH<6, and is mostly likely to retain activity in solutions with a pH between 6-9.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
产品编号 D2650 | CAS号 67-68-5 | SIGMA
Frequently Asked Questions
Frequently Asked Questions are available for this Product.
Application
DMSO 是一种用于化学反应（如聚合酶链式反应 (PCR)）的极性非质子溶剂，也可作为冷冻保护玻璃
Caution
容易过度冷却，并在室温下缓慢融化固化的产品放在室温
Other Notes
This product is a Hybri-Max product. It is hybridoma tested and is assessed for suitability in cell freezing. This product is sterile filtered (0.2 micron) and tested for endotoxin levels.
包装:5mL 和 10mL 火焰封口安瓿瓶包装，100mL 棕色瓶包装
产品编号 A9415 | CAS号 50-76-0 | SIGMA
Frequently Asked Questions
Frequently Asked Questions are available for this Product.
Application
Actinomycin D is an antineoplastic antibiotic that inhibits cell proliferation with wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumour and the sarcomas. Recommended for us in cell culture applications at 1μg/mL.
Caution
This product is hygroscopic and light-sensitive. If stored protected from light and moisture at 2-8°C, it remains unchanged, by HPLC testing, for at least 15 months. Unused dilute solutions of Actinomycin D are extremely sensitive to light and tend to adsorb to plastic and glass and should be discarded. However, frozen aliquots of concentrated stock solution are stable for at least a month.
包装：2, 5, 10, 25 mg in glass bottle
Preparation Note
Actinomycin D is sold as red, shiny crystals and is soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL. Some references also show slight solubility in water of 0.5 mg/mL.
Biochem/physiol Actions
Actinomycin D inhibits the proliferation of cells by forming a stable complex with double-stranded DNA, inhibiting DNA-primed RNA synthesis and causing single-stranded breaks in DNA. It has been shown to be an inhibitor of the minus-strand transfer step in reverse transcriptase.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Sigma人血管紧张素 II
产品编号 A9525 | CAS号 4474-91-3 | SIGMA
Angiotensin II human ≥93% (HPLC), powder
| CAS号 4474-91-3 分子式: C50H71N13O12 分子量 1046.18 assay ≥93% (HPLC) form powder total impurities 1.2-10.4% acetate storage temp. -20°C Amino Acid Sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Antibody Adsorbant Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH · 2CH3COOH · H2O Analysis Note 肽含量不低于 75% Biochem/physiol Actions 血管紧张素 (Ang) II 在调节心血管的血液动力学和结构中起重要作用。Ang II 在成人组织内的大部分已知效应均可归因于血管紧张素 II 类型 I (AT1) 受体。AT1 和 AT2 受体在药理学和生物化学性质上有差别，在心血管血液动力学和细胞生长方面表现出相反的效应。此外，肾素-血管紧张素和一氧化氮生成系统在心血管功能的调节中显示出相互作用的现象。Ang II 刺激血管生成，增加微血管密度。事实上，血管紧张素 II 是由血管紧张素转换酶对血管紧张素原的作用而生成；C-端-组氨酰-亮氨酸裂解。 |
|
| 保存条件： | -20°C |
Sigma 孕酮Progesterone
产品编号 P8783 | CAS号 57-83-0 | SIGMA
英文名:Progesterone
中文名:1.孕甾酮 2.黄体酮 3.黄体素 4.孕酮 5.孕醇 6.黄体激素
Synonym: 4-Pregnene-3,20-dione
CAS Number 57-83-0
Empirical Formula (Hill Notation) C21H30O2
Molecular Weight 314.46
description:synthesized from materials derived from plant source
product line:BioReagent
form:powder
potency:0.1-20 ng/mL
mp:128-132 °C(lit.)
solubility :absolute ethanol: soluble1 mg/mL
suitability :uitable for cell culture
Application
用于细胞培养，研究细胞信号传导和基因表达的甾醇调控
Other Notes
由卵巢黄体产生的类固醇激素。
包装：1, 5, 25 g in glass bottle
Reconstitution
To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.
Physical form
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与
产品编号 A3803 | CAS号 9048-46-8 | SIGMA
包装：10, 50, 100 g in poly bottle
Preparation Note
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn[] method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term “Fraction V” has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.
采用热休克分级分离法制备。经过进一步纯化以降低脂肪
Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.
| Related Categories | Albumin, Bovine Serum Albumins, Heat Shock Fractionated, 生化试剂, 蛋白质及衍生物 更多… |
| assay | ≥98% (agarose gel electrophoresis) |
| form | lyophilized powder |
| mol wt | mol wt ~66 kDa |
| purified by | heat shock fractionation |
| packaging | poly bottle of |
| origin | USA origin |
| impurities | ≤0.005% Fatty acids |
产品编号 A8806 | CAS号 9048-46-8 | SIGMA
包装：1, 5 g in poly bottle
Preparation Note
Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn[] method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term “Fraction V” has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.
通常称为 Cohn fraction V；本品采用改进的 Cohn 氏冷乙醇分级分离法制备。
Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.[]
Protocols & Applications
Select the right albumin for your application with the Albumin Selection Guide
| Related Categories | Albumin, Albumins, Albumins and Transport Proteins,Albumins by Application, Bioactives and Supplements for Stem Cell Expansion, |
| Quality Level | PREMIUM |
| product line | BioReagent |
| assay | ≥96% (agarose gel electrophoresis) |
| form | lyophilized powder |
| mol wt | mol wt ~66 kDa |
| purified by | cold ethanol fractionation |
| packaging | poly bottle of |
产品编号 T8387 | CAS号 68517-67-9 | SIGMA
包装：1, 5, 15 g in poly bottle
Physical form
Lyophilized powder stabilized with lactose and dextran
Application
Thiopropyl Sepharose® 6B is used in protein chromatography, affinity chromatography and hydrophobic interactions. Thiopropyl Sepharose® 6B has been used for the removal of inhibitors from PCR extracts from evidence collected for law enforcement murder investigations. Thiopropyl Sepharose® 6B has also been used to describe a method for the investigation of functional properties of distinct domains of viral thiol proteins, including the influenza virus membrane M1 protein.
法律信息
Sepharose is a registered trademark of GE Healthcare
Sigma 阿霉素 盐酸盐
产品编号 D1515 | CAS号 25316-40-9 | SIGMA
Frequently Asked Questions
Frequently Asked Questions are available for this Product.
包装:10 mg in glass bottle Biochem/physiol Actions
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
法律信息
Adriamycin 为以下机构的注册商标： RDF Pharmacia & Upjohn S.P.A.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
| Related Categories | Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, |
| assay | 98.0-102.0% (HPLC) |
| mp | 216 °C (dec.)(lit.) |
| solubility | H2O: soluble50 mg/mL, clear |
| Mode of action | DNA synthesis | interferes |
| antibiotic activity spectrum | viruses |
| storage temp. | 2-8°C |