Hampton Solubility & Stability Screen

Hampton Solubility & Stability Screen

Solubility & Stability Screen(溶解度和稳定性的屏幕)
应用:溶解性和稳定性屏幕的设计,以协助识别解决方案的条件,促进蛋白质的溶解性和稳定性,并尽量减少蛋白质沉淀。
Solubility & Stability Screen
Solubility & Stability Screen
Solubility & Stability Screen
Solubility & Stability Screen HR2-072
Applications

A solubility screen, a stability screen, an additive screen for protein assays including ThermoFluor and crystallization
Preformulation screening

 

Compatible with Thermofluor , Differential Scanning Fluorimetry (DSF), and Protein Thermal Shift assays
96 sterile filtered reagents
17 classes of reagents and excipients
Highly concentrated (10x) reagent formulation
Developed at Hampton Research

Features
Methodologies

Thermal shift assay
Dynamic Light Scattering
Use Solubility & Stability Screen along side Slice pH and Solubility & Stability Screen 2 to optimize sample buffer
Description

Solubility & Stability Screen is designed to assist in the identification of solution conditions which promote protein solubility and stability, and minimize protein precipitation. Solubility & Stability Screen is a solubility screen, a stability screen, and may also be used as an additive screen in the presence of a crystallization reagent.
The Hampton Research Solubility and Stability Screen can evaluate protein solubility, stability and crystallization in the presence of 94 different chemical additives sampling 17 different classes of reagents plus two controls.
Protein solubility and stability are universally required in a wide range of applications, including general biochemical studies, the preparation of proteins in pharmaceuticals, structural biology and crystallization.1-11The preparation of a concentrated, soluble and stable protein sample can often be a difficult task as proteins often aggregate, precipitate or denature.
Thermofluor (also known as Differential Scanning Fluorimetry, DSF and Protein Thermal Shift) provides a rapid, convenient and effective means of identifying subsaturating solution conditions that may also correlate with protein heterogeneity and poor crystallization outcomes.12
Protein solubility and stability is affected by many different chemical factors including pH, buffer type, chemical additives and excipients. pH and buffer type are dominant protein solubility and stability variables and can be evaluated and optimized using the Hampton Research Slice pH kit HR2-070. Slice pH evaluates protein solubility, stability and crystallization versus 20 different buffers over the pH range 3.5-9.6. Chemical additives influencing protein solubility and stability can be evaluated using the Solubility & Stability Screen.
It is widely accepted that protein solubility and stability can be increased by the use of chemical additives.5,15Seventeen classes of reagents are sampled by the Solubility & Stability Screen and each of these classes has been reported as important in improving sample solubility and stability.2-11
The Solubility & Stability Screen is a set of 94 high purity reagents formulated in high purity water (NCCLS/ASTM Type 1+) at 25°C and are 0.22 micron sterile filtered. The 94 solubility and stability reagents are formulated at 2 to 10 times their recommended working concentration. The remaining two reagents are water and a negative (TCA) control. A water control demonstrates the effect of diluting sample as well as sample buffer concentration. TCA, the negative control, demonstrates total sample precipitation, loss of sample solubility and loss of sample stability. The effects of the Solubility & Stability reagents can be compared with this negative control to assist in the identification of reagents promoting sample solubility and stability. 500 microliters of each reagent is supplied in a sterile 96 well polypropylene Deep Well block. The Solubility & Stability Screen reagents are compatible with the sitting or hanging drop vapor diffusion, microbatch, free interface diffusion, sandwich drop vapor diffusion, and dialysis crystallization methods utilizing water soluble reagents.

Hampton50号毛细管Glass Number 50 Capillaries

Hampton50号毛细管Glass Number 50 Capillaries
Glass Number 50 Capillaries

应用:
  X-ray data collection
  Liquid-liquid diffusion crystallization
  Gel acupuncture crystallization
Features
  Glass Number 50 (borosilicate)
  Thin walled – 10 micron
      上海金畔生物作为Hampton蛋白结晶产品的代理商,竭诚为您服务,欢迎新老客户咨询。

Description 描述
Glass Number 50 (borosilicate glass) capillaries that are extremely thin walled (approximately 10 micron wall thickness). The length of the capillary has a well defined diameter, with one end having a funnel shape and the other end closed. Glass capillaries have a wall thickness of 0.01 mm and an overall length of 80 mm +/- 5 mm. Glass capillaries are available in a wide range of outside diameters from 0.1 mm to 2.0 mm. They are designed to mount, hold, and store small molecule and biological macromolecular crystals for x-ray data collection. Capillaries can also be used for crystal density measurements and crystal growth experiments. The capillaries can be sealed tightly against moisture and gases using wax, epoxy, or other sealing materials.
In determining what glass or quartz capillary is right for you, please refer to the “Linear Absorption Coefficient µ cm-1” table. This table indicates the amount of radiation that is absorbed by the capillary during x-ray data collection.
For 0.1 mm to 2.0 mm capillaries the open end capillary tube base size is 3.0 +/- 0.15 mm OD x 0.13 +/- 0.10 mm Wall thickness.
The Diameter is measured 40 mm from the closed end. The tolerances are as follows
Glass Number 50 Capillaries
Glass Number 50 Capillaries
 

0.1 mm -0.075 / +0.075 mm
0.2 mm -0.050 / +0.050 mm
0.3 mm -0.050 / +0.100 mm
0.4 mm -0.100 / +0.100 mm
0.5 mm -0.100 / +0.100 mm
0.6 mm -0.100 / +0.100 mm
0.7 mm -0.150 / +0.150 mm
0.8 mm -0.150 / +0.150 mm
0.9 mm -0.150 / +0.150 mm
1.0 mm -0.150 / +0.250 mm
1.5 mm -0.250 / +0.250 mm
2.0 mm -0.250 / +0.250 mm
Capillaries have only been tested at atmospheric pressure (760 mmHg (torr), 29.92 inHg, 14.696 psi). Use at other pressures has not been tested.
Sigma代理  Abcam代理  CST代理  Santa Cruz代理  Biolegend代理 ebioscience代理  Invitrogen代理   millipore代理  BD流式抗体代理   GeneTe x抗体代理  Novus抗体代理   R&D代理 Biovison代理  Jackson代理  MBL抗体代理  ProSpec抗体代理  Bethyl抗体代理  Antibody Revolution抗体代理  Torrey Pines Biolabs代理  Amresco代理  MPbio代理  Laysan bio代理  NANOCS代理  Avanti代理  wako代理  lumiprobe代理(活性荧光染料)   NEB酶代理  Roche酶代理  Toyobo酶代理   USP代理  EP代理  Dr代理  TRC代理  TCI代理  Reagecon代理 Megazyme代理 Hampton代理(蛋白结晶) whatman代理(滤膜滤纸) GE代理(蛋白纯化) Corning康宁代理  Axygen代理 Falcon代理  NISSUI日水代理 Himedia代理 OXOID代理  BD培养基代理 Ludger代理(糖蛋白分析产品)  Eppendorf代理  Labnet代理  标准品代理 抗体代理 酶试剂代理  培养基代理 耗材代理 Elisa试剂盒代理 。

Hampton 水晶透明密封带Crystal Clear Sealing Tape

Hampton 水晶透明密封带Crystal Clear Sealing Tape
Crystal Clear Sealing Tape
3 inch, 1.88 inch, 1.88 inch with dispenser, 0.75 inch with dispenser (left to right)
Crystal Clear Sealing Tape
0.75 inch Crystal Clear Sealing Tape
Applications  应用
Sealing tape used to seal sitting drop crystallization experiments
Description
These optically clear tapes are compatible with protein crystallization reagents. The polypropylene Crystal Clear Sealing Tapes use acrylic solvent based adhesives which are compatible with aqueous crystallization reagents.
Catalog number HR3-511 is a 1.88 inch (48 mm) wide, 3 mil tape on a 43.7 yard (40 M) roll with a 1.5 inch core and is supplied with a green dispenser / cutter.Catalog number HR4-511 is a 1.88 inch wide, 3 mil tape on a 60 yard roll with a 3 inch core and no dispenser / cutter.Two strips of the HR3-511 or HR4-511 will seal a Corning, Cryschem, CrystalClear Strip, Greiner, Intelliplate, Linbro, Swissci (MRC), VDX and VDXm plate.Catalog number HR4-506 is a 3 inch wide, 3 mil tape on a 54.86 yard roll with a 3 inch core and no dispenser / cutter.One strip of the HR4-506 will seal a Corning, Cryschem M, CrystalClear Strip, Greiner, Intelliplate, Swissci (MRC) and VDXm plate.Crystal Clear Mini Sealing Tape HR4-508 is a 0.75 inch (19 mm) wide, 3 mil tape on a 650 inch (16.5 M) roll and is supplied with a clear dispenser / cutter. The tape is useful for resealing or patching wells after mounting crystals. The tape is also wide enough to seal a single row of a Cryschem S or Cryschem M plate.See chart for tape and plate compatibility.

Hampton热销产品

Hampton Research是 美国最权威的蛋白结晶试剂盒提供商,产品齐全,性价比高。
在生命科学领域,上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。庆祝上海金畔生物正式成为Hampton的签约代理商,在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱,我们将一如既往的为广大客户带来Hampton高品质的产品和服务,欢迎广大新老客户来电咨询。‘
美国Hampton Research公司位于加利福尼亚州,是一家专门从事蛋白质晶体研究的生产商。该公司向全球科研人员提供全面的晶体研究试剂和相关实验耗材,同时提供晶体设计和合成方面的定制服务。Hampton Research公司以其先进的生物大分子结晶技术和广泛实用的产品线,不仅为全世界晶体研究人员的工作带来了便捷,而且也受益于科研人员的回馈不断发展自己,目前已成为晶体研究领域最受信赖的品牌之一。
Hampton research主要产品:
Crystallization Screens 用于筛选和优化蛋白质/多肽/核酸结晶的一系列经验证的高精配方型溶液
Optimize Reagents 结晶级别盐类,聚合物,有机溶液或缓冲液
Crystallization Plates, Hardware & Accessories 结晶板(悬滴法和坐滴法,微量透析,微配液,自由界面扩散,凝胶以及无容器悬浮法)及其他配件
Cryocrystallography 低温晶体学耗材如 Crystalcap system,cryoloops
Goniometer Heads&Supplies 测角器头和配件
Protein Crystallization Standards 结晶级别标准蛋白
Custom Shop Crystallization Reagents 定制试剂盒和结晶溶液内的单一组分
StockOptions Kits 内含盐类,缓冲液和冷冻液的简便型试剂盒
Tools,Seeding&Resin 结晶用探针,结晶笔,seeding法结晶工具
Capillary Mounts & Supplies 毛细管,玻璃纤维, 蜡,黏合剂和密封剂
Hampton热销产品

  • StockOptions pH Buffer Kit HR2-241
    Crystallization grade buffer stocks for crystal screening, optimization, & production
    Crystal Screen Cryo HR2-122
    Primary screen with cryo for proteins, soluble peptides, nucleic acids, & water soluble small molecules
  • Natrix HR2-116
    Primary biased sparse matrix crystallization screen for nucleic acids & protein/nucleic acid complexes
  • MembFac HR2-114
    Primary sparse matrix crystallization screen for membrane proteins and samples with limited solubility
  • SaltRx HR2-136
    Primary or secondary, salt and pH matrix crystallization screen for biological macromolecules
  • Grid Screens HR2-248
    Primary or secondary, salt, polymer, organic and pH grid crystallization screen for biological macromolecules
  • PEG/Ion HR2-126
    Primary or secondary, polymer, salt and pH matrix crystallization screen for biological macromolecules
  • PCT™ Pre-Crystallization Test HR2-140
    Determine the appropriate sample concentration for crystallization screening
  • Index HR2-144
    Primary, diverse reagent system crystallization screen for proteins, complexes, peptides, nucleic acids, & water soluble small molecules
  • Crystal Screen HR2-110
    Primary screen for proteins, soluble peptides, nucleic acids, & water soluble small molecules;Sparse matrix additive screen
  • PEGRx HR2-082
    Primary and secondary, polymer and pH based crystallization screen for biological macromolecules
  • Additive Screen HR2-428
    Manipulate sample-sample & sample-solvent interactions to improve crystals or alter sample solubility
  • Detergent Screen HR2-408
    Prevent and manipulate non-specific aggregation due to hydrophobic interactions
  • CryoPro HR2-073
    Water soluble cryoprotectant reagent set designed for the cryopreservation of biological macromolecular crystals
  • StockOptions Salt HR2-245
    Crystallization grade salt reagent stock solutions for screen formulation and optimization
  • Siliconized Glass Cover Slides HR3-217
    Hanging, sitting or sandwich drop crystallization
  • Intelli-Plate 96 HR3-185
    蛋白结晶座滴板
  • CrystalCap HR4-733
  • CryoLoop HR4-623

    • CryoTong™ – Long HR5-104
      Crystal transfer under cryo temperature
    • CrystalWand™ Magnetic HR4-729
      CrystalCap Magnetic & CrystalCap Copper Magnetic handling tool
    • Vial Clamp™ – Straight HR4-670
      Vial support and manipulation
    • CrystalCap™ Holder HR4-707
    • CryoCane HR4-709
      Organized storage of CrystalCaps

Hampton CrystalEX Second Generation (Corning)

Hampton CrystalEX Second Generation (Corning)
Crystal<i>EX</i> Second Generation (Corning)
CrystalEx Plates
Applications
   Sitting drop crystallization
Features

96 well sitting drop plate
Round and conical flat bottom drop well shapes
1, 2 or 4 microliter drop wells
1, 3 or 5 drop wells per reservoir
Hydrophilicity treated or untreated
PZero or COC plate material–UV imaging compatible

Description
The second generation of Corning® 96 Well, sitting drop format plates are built to SBS specifications, making them well suited for high throughput crystallization and are fully compatible with robotic equipment. The plates are available in several different configurations with varying drop well shapes, plate materials, and number of drop wells per reagent well. The basic plate design is one reagent well flanked by one or three drop wells, with SBS standard spacing between the centers of adjacent well clusters. One may choose a plate with small (1 µl), medium (2 µl), or large (4 µl) drop well volumes. The choice of round or conical flat well shapes are available. The PZero polymer provides for zero background polarization and is non-birefringent. PZero plates are not treated. The COC polymer offers high chemical resistance. Both types of plastic feature improved transparency. The reservoir numbers are embossed on each individual well for easy identification. Drop well locations conform to SBS standards for robotic handling. The low-volume reagent well saves on reagent costs. The plates can be sealed using Crystal Clear Sealing Film (HR3-609), 3 inch wide Crystal Clear Sealing Tape (HR4-506) or ClearSeal Film™ (HR4-521).
Corning has discontinued 3557 – special pricing and limited inventory available for this item only.

CAT NO NAME DESCRIPTION
HR8-135 Corning 3556 4µl round drop well, 1 drop well, COC, untreated – 10 plate case
HR8-134 Corning 3556 4 µl  round drop well, 1 drop well, COC, untreated – 40 plate case
HR8-137 Corning 3551 4 µl conical flat drop well, 1 drop well, COC, treated – 10 plate case
HR8-136 Corning 3551 4µl conical flat drop well, 1 drop well, COC, treated – 40 plate case
HR8-139 Corning 3552 2 µl round drop well, 3 drop well, COC, untreated – 10 plate case
HR8-138 Corning 3552 2µl  round drop well, 3 drop well, COC, untreated – 40 plate case
HR8-141 Corning 3553 2 µl conical flat drop well, 3 drop well, COC, untreated – 10 plate case
HR8-140 Corning 3553 2 µl conical flat drop well, 3 drop well, COC, untreated – 40 plate case
HR8-147 Corning 3550 1µll conical flat drop well, 3 drop well, COC, untreated – 10 plate case
HR8-146 Corning 3550 1µl conical flat drop well, 3 drop well, COC, untreated – 40 plate case
HR8-160 Corning 3557 1 µl conical flat drop well, 5 drop well, PZero – 10 plate case
HR8-158 Corning 3557 1 µl conical flat dro p well, 5 drop well, PZero – 40 plate case

Hampton Polyethylene glycol 4,000

Hampton Polyethylene glycol 4,000

Applications
Crystallization grade Polyethylene glycol for formulating screens or for optimizatio
Features
Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)

Description
Polyethylene glycol 4,000
Synonym: PEG 4,000
H(OCH2CH2)nOH
Mr 3,500-4,500
CAS Number [25322-68-3]
EC Number 500-038-2
Merck 14,7568
RTECS TQ3500000
MDL Number MFCD00081839
PubChem Substance ID 24890217
Melting point (Starting Material) 58.0-61.0°C
Aldehyde None detected
Peroxide None detected

HR2-529 Measured pH range: 6.9 – 9.5 at 25°C
HR2-529 Measured Conductivity Range: 35.3 – 46.9 µS/cm at 25°C
HR2-529 Measured Refractive Index Range: 1.40172 – 1.40279 at 20°C

CAT NO NAME DESCRIPTION
HR2-605 Polyethylene glycol 4,000 Flake – 500 g
HR2-529 Polyethylene glycol 4,000 50% w/v solution – 200 ml

Hampton 蛋白结晶优化试剂 Optimization Screens

Hampton 蛋白结晶优化试剂 Optimization Screens

1、Solubility & Stability Screen  蛋白特异性试剂优化溶解性和稳定性
Protein specific agents for optimization of solubility & stability  
2、Solubility & Stability Screen 2   离子缓冲液
Buffer, pH & ionic strength screen for optimization of solubility & stability
3、Slice pH    PH缓冲液
pH & buffer screen for optimization of crystals or sample solubility & stability
4、Additive Screen  96孔板添加剂试剂盒
96 compound screen for optimization of crystal size & quality
5、Silver Bullets • Silver Bullets Bio
Small molecule additive screen for optimization of crystal size & quality
6、Detergent Screen
Detergent screen for optimization of crystals or sample solubility & stability
7、Ionic Liquid Screen
Ionic liquid additive screen for optimization of crystal size & quality
8、StockOptions Buffer Kits
Titrated buffer sets for optimization of crystals or sample solubility & stability
9、StockOptions Polymer
n of crystal size & quality
10、StockOptions Salt
Salt reagent kit for optimization of crystal size & qualit
11、Polymer reagent kit for optimizatioy
Proti-Ace
In situ proteolysis kit protein for crystallization screening & optimization
12、Reductive Alkylation
Reductive alkylation kit for crystallization screening & optimization
13、Silica Hydrogel Kit
pH neutral silica hydrogel matrix crystallization
14、Low Melting Agarose
Agarose gel matrix crystallization
15、CryoPro
Water soluble cryoprotectant reagent set
16、Heavy Atom Screens
Heavy atom kits for multiple isomorphous replacement
17、I3C Phasing Kit
Produce heavy atom derivative of biological macromolecules for phasing

Hampton 48孔坐滴蛋白结晶板 48-Well Crystallization Plate

Hampton 48孔坐滴蛋白结晶板 48-Well Crystallization Plate
Applications

Sitting drop crystallization
Features

One drop per reservoir
SBS format
48 well plate
9 mm standard distance between wells
Drop volume: Up to 10 µl
Reservoir volume: 50 to 200 µl
Micro-numbering alongside drop volumes
Rigid plate structure
Wide partition walls between wells improve sealing
Developed in conjunction with the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom
UV compatible (UVP)
Description
MRC Maxi 48-Well Crystallization Plate for Automated Optimization
The MRC Maxi optimization plate is a breakthrough for macromolecular crystallization presented in a 48 well format. Offering easy to automate crystallization optimization with large sitting-drops, the new MRC Maxi Crystallization plate is the perfect solution. Manufactured by Swissci AG, the plate offers an SBS format while providing 48 wells. MRC Maxi is intended for large drops and is compatible both with standard robotic systems as well as manual pipetting.
The plate was developed at the MRC Laboratory of Molecular Biology (Cambridge, UK) in collaboration with Jan Löwe and Fabrice Gorrec. It is a result of many years of experience in successful robotic high-throughput crystallization and complements the original MRC crystallization plate, which is intended for smaller drop volumes and higher throughput during screening.
Drop volumes of up to 10 µl are possible. The 9 mm standard distance between wells is preserved, enabling the use of multi-channel manual pipettes and robotic liquid handlers, making MRC Maxi one of the most automation-friendly optimization plates on the market.
MRC Maxi is covered by global intellectual property and design registration as are the Swissci AG MRC 2 lens 96 well plates. Several breakthrough features of the original MRC plate have been maintained. Wells are labeled individually. Drops are raised for easy access during crystal retrieval. MRC Maxi uses the same proprietary polymer specially selected for the purpose of UV light visualization and the material used keeps through-plastic evaporation to a minimum. Well shapes are spherical but shallow.
The MRC Maxi Crystallization plate offers unique properties that make it the ideal choice for microliter-sized optimization experiments and is made from UV compatible UVP.
The advantages of the MRC Maxi Crystallization plate – in brief
Easy Crystal Retrieval
Raised wide wells make the crystal mounting especially easy.
Easy Viewing
The wells are wide conical.
Each well has a micro lens for perfect illumination.
Micro numbering readable under the microscope for each well.
The optically superior polymer (UVP) is UV transmissible.
Better Sealing
Wide partition walls between the wells give plenty of area for good sealing with tape.
Very Rigid, Automation-Friendly Plate Design
The UVP polymer reduces through-plastic evaporation to a minimum.
SBS Standard
The plates are designed to the SBS standard and are compatible with all common holders.
9 mm distance from well-to-well within columns, 18 mm distance within rows.
Unique Polymer (UVP)
Ultra-low sample binding.
No static charging.
Recommended Volumes
Volumes validated for MRC Maxi are up to 10 µl of sample drop and 200 µl of the crystallization reagent.
CAT NO NAME DESCRIPTION
HR3-179 MRC Maxi 48-Well Crystallization Plate 10 plate case
HR3-180 MRC Maxi 48-Well Crystallization Plate 40 plate case

Hampton蛋白结晶产品目录

Hampton蛋白结晶产品目录

产品编号 中文品名 英文品名
HR4-126 11 刀片替换装 Replacement #11 Blade
HR4-904 CrystalCap Magnetic Vial CrystalCap™, Vial only
HR4-729 CrystalWand Magnetic, Straight CrystalWand™ Magnetic, Straigh
HR4-837 Micro-Tools II Set Micro-Tools II™ Set
HR4-811 Micro-Tools Set Micro-Tools™ Set
HR3-172 VDX 24孔板,带密封剂 VDX™ Plate, with sealant
HR4-902 带磁力底座 CrystalCap™, without Vial
HR4-733 带磁力底座 CrystalCap™, with Vial
HR4-745 带铜管磁力底座 CrystalCap™ Copper 18 mm, with
HR4-708 冻存套 CryoSleeve™
HR3-217 硅化方形盖玻片22mmx0.22mm 22 mm x 0.22 mm Siliconized Sq
HR4-671 夹钳-弯 Vial Clamp™ – Curved, 45°/135°
HR4-670 夹钳-直 Vial Clamp™ – Straight
HR4-316 Super Glue
HR4-506 胶带 3 inch wide x 55 yard Crystal
HR3-083 结晶板 2孔 MRC 2 Well Crystallization Pla
HR3-125 结晶板 3孔 3 Well Crystallization Plate (
HR4-217 晶体探针 Crystal Probe
HR4-662 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-673 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-674 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR4-675 泡沫保温瓶 Spearlab Cryogenic Foam Dewar
HR1-008 液氮罐 CX100 (含运输箱) CX100 Cryo-Express Dry Shipper
HR2-912-37   Crystal Screen 2™ #37
HR2-501   50% v/v Jeffamine® M-600® pH 7
HR2-509   1.0 M BICINE
HR2-517   100% Polyethylene glycol 300
HR2-523   50% w/v Polyethylene glycol 1,
HR2-525   50% w/v Polyethylene glycol 1,
HR2-529   50% w/v Polyethylene glycol 4,
HR2-533   50% w/v Polyethylene glycol 6,
HR2-537   1.0 M Magnesium formate dihydr
HR2-541   3.5 M Ammonium sulfate
HR2-545   2.0 M Lithium sulfate monohydr
HR2-547   7.0 M Sodium formate
HR2-549   1.6 M Sodium citrate tribasic
HR2-551   4.0 M Sodium phosphate monobas
HR2-557   2.0 M Calcium chloride dihydra
HR2-563   1.0 M Zinc acetate dihydrate
HR2-102   StockOptions™ Hepes
HR2-103   StockOptions™ Bis-Tris Propane
HR2-104   StockOptions™ Citric Acid
HR2-106   StockOptions™ Bis-Tris
HR2-107   SaltRx™ 1
HR2-109   SaltRx™ 2
HR2-110   Crystal Screen™
HR2-112   Crystal Screen 2™
HR2-114   MembFac™
HR2-116   Natrix™
HR2-117   Natrix™ 2
HR2-118   Nucleic Acid Mini Screen™
HR2-126   PEG/Ion Screen™
HR2-235   StockOptions™ Sodium Citrate
HR2-237   StockOptions™ Tris Hydrochlori
HR2-239   StockOptions™ Sodium Cacodylat
HR2-241   StockOptions™ pH
HR2-245   StockOptions™ Salt
HR2-249   StockOptions™ Succinic Acid
HR2-320   Seed Bead™
HR2-406   Detergent Screen HT™
HR2-428   Additive Screen™
HR2-434   Reductive Alylation Kit
HR2-442   Heavy Atom Screen™ Pt
HR2-444   Heavy Atom Screen™ Au
HR2-446   Heavy Atom Screen™ Hg
HR2-448   Heavy Atom Screen M1™
HR2-450   Heavy Atom Screen M2™
HR2-082   PEGRx™ 1
HR2-084   PEGRx™ 2
HR2-096   Silver Bullets™
HR2-098   PEG/Ion 2 Screen™
HR4-315   CrystalWand™ Magnetic, 45° McM
HR4-350   Large Applicator (200 & 350 µl
HR4-625   Mounted CryoLoop™ – 20 micron,
HR4-637   CryoTong™ 18 mm (standard 110
HR4-709   CryoCane™ 5 Vial Holder
HR4-711   CryoCane™ 6 Vial Holder
HR2-211   Grid Screen™ Ammonium Sulfate
HR2-213   Grid Screen™ PEG 6000
HR2-227   StockOptions™ Polymer
HR2-233   StockOptions™ Sodium Acetate
HR4-931   CryoLoop™ – 20 micron, 0.2 – 0
HR4-945   Mounted CryoLoop™ – 20 micron,
HR4-947   Mounted CryoLoop™ – 20 micron,
HR4-953   Mounted CryoLoop™ Sampler – 20
HR4-955   Mounted CryoLoop™ – 20 micron,
HR4-957   Mounted CryoLoop™ – 20 micron,
HR4-959   Mounted CryoLoop™ – 20 micron,
HR4-961   Mounted CryoLoop™ – 20 micron,
HR4-963   Mounted CryoLoop™ – 20 micron,
HR4-970   Mounted CryoLoop™ – 20 micron,
HR4-971   Mounted CryoLoop™ – 20 micron,
HR4-989   CryoLoop™ – 10 micron, 0.3 – 0
HR2-128   Crystal Screen Lite™
HR2-138   Additive Screen HT™
HR2-140   PCT™ – Pre-Crystallization T
HR4-313   Mounted CryoLoop™ – 20 micron,
HR2-601   100% Polyethylene glycol 200
HR2-607   50% w/v Polyethylene glycol 10
HR2-609   30% w/v Polyethylene glycol 20
HR2-611   100% Polyethylene glycol monom
HR2-613   50% w/v Polyethylene glycol mo
HR2-615   50% w/v Polyethylene glycol mo
HR2-625   6.0 M 1,6-Hexanediol
HR2-637   5.0 M Sodium chloride
HR2-723   1.0 M BICINE pH 9.0
HR2-755   100% Tacsimate™ pH 7.0
HR2-761   3.0 M DL-Malic acid pH 7.0
HR2-801   TCEP hydrochloride
HR2-821   2.0 M Magnesium sulfate heptah
HR2-829   100% Tacsimate™ pH 8.0
HR2-857   4.0 M TMAO
HR2-859   100% Polyethylene glycol 600
HR2-910-08   Crystal Screen™ #08
HR2-144   Index™
HR4-993   Mounted CryoLoop™ Sampler – 10
HR4-995   Mounted CryoLoop™ – 10 micron,
HR4-999   Mounted CryoLoop™ – 10 micron,
HR6-146   1.0 mm Quartz Capillary
HR8-034   Cryo Puck Carrier
HR8-035   Porcupine Push Tool
HR8-036   Puck Wand
HR8-037   Cryo Puck Base Removal Platfor
HR8-038   Angled Cryo Puck Tong
HR8-039   Cryo Puck Dewar Loading Tool
HR8-114   CrystalCap HT™, Vial only
HR8-133   Seeding Tool
HR8-173   CrystalCap™ Copper HT, 0.025 –
HR8-174   CrystalCap™ Copper HT, 0.05 –
HR8-175   CrystalCap™ Copper HT, 0.1 – 0
HR8-176   CrystalCap™ Copper HT, 0.2 – 0
HR2-575   1.0 M Sodium cacodylate trihyd
HR2-581   1.0 M Hydrochloric acid

Hampton Natrix • Natrix 2 • Natrix HT

Hampton Natrix • Natrix 2 • Natrix HT

Applications
  Primary biased sparse matrix crystallization screen for nucleic acids & protein/nucleic acid complexes  主要用于核酸和蛋白质/核酸复合物的删选
Features

Nucleic acid sparse matrix screen
Sparse matrix formulation efficiently samples salts, polyols, polymers, organics, additives & pH
pH range 5.6 – 8.5
Tube or Deep Well block format
 Description
Natrix, Natrix 2 and Natrix HT are based upon published reagent formulations for the crystallization of nucleic acids and protein-nucleic acid complexes. A variety of hammerhead ribozymes and other ribozymes, RNAs, DNAs, RNA-drug complexes, and RNA-protein complexes have been crystallized using the Natrix protocols.By using sparse matrix sampling technology, The Natrix kits allow one to quickly test wide ranges of pH, salts, and precipitants using a very small sample of nucleic acid.
Natrix screens are unique in that rather than relying solely on the traditional nucleic acid precipitant MPD, Natrix screens also utilize Polyethylene glycols (PEGs) in a variety of molecular weights (200, 400, 4,000, 8,000) as well as 2-Propanol, Polyethylene glycol monomethyl ether (PEG MME), and 1,6-Hexanediol. Many of the polymeric and low molecular weight organic precipitants are combined with various monovalent salts as precipitating agents. This combination of salts and low molecular weight organics and polyalcohols, as well as the utilization of varying chain length PEGs, has proven to be a successful combination for producing nucleic acid and protein-nucleic acid complex crystals.
Natrix contains 48 unique reagents, 10 ml each and is based on the sparse matrix formulation first described by William Scott in 1995.
Natrix 2, an extension of Natrix, contains 48 unique reagents, 10 ml each. Natrix 2 is a biased sparse matrix screen based on extracting patterns from crystallization data as well as reagent formulations first described by Berger et al in 1996.
Natrix HT contains 1 ml of each reagent from Natrix and Natrix 2 in a single Deep Well block format.
Ready-to-use reagents are sterile filtered and formulated with ultra-pure Type 1 water, using the highest purity salts, polymers, organics and buffers. Individual reagents are available through the Hampton Research Custom Shop.
Natrix • Natrix 2 • Natrix HT
Natrix • Natrix 2 • Natrix HT
View Full Size
Natrix • Natrix 2 • Natrix HT

 

CAT NO NAME DESCRIPTION
HR2-116 Natrix 10 ml, tube format
HR2-117 Natrix 2 10 ml, tube format
HR2-131 Natrix HT 1 ml, Deep Well block format

Hampton 24孔悬滴板 VDX Plate with sealant(带密封剂)

Hampton 24孔悬滴板 VDX Plate with sealant(带密封剂)
VDX Plate with sealant
Applications

Hanging drop crystallization
Sitting drop crystallization with Micro-Bridges® or Glass Sitting Drop Rods™
Dialysis crystallization with Dialysis Buttons™
Features

24 well plate with raised cover
Sealant applied to 24 wells, ready to seal with cover slides
Compatible with 22 mm diameter square and circle cover slides
Optically clear plastic
Extremely versatile and cost-effective crystallization platform
Compatible with UV crystal imaging when used with HR3-231 and HR3-233 – 22 mm x 0.22 mm Siliconized circle cover slides and HR3-215 and HR3-217 – 22 mm x 0.22 mm Siliconized square cover slides

Description
24 well crystallization plate for hanging drop or sitting drop vapor diffusion crystallization (when used with Micro-Bridges or Glass Rods), or dialysis crystallization (when used with Dialysis Buttons). Stackable, optically clear plastic 24 well plates with raised covers (to allow room for cover slides) and flat bottoms for exceptional optics. Raised, wide rings around each reservoir (well) minimize cross contamination and allow each well to be individually sealed with 22 mm diameter circle or square cover slides. Plates are individually wrapped and supplied with applied sealant. 15.0 cm x 10.8 cm plate footprint is convenient for manual pipetting and well access while at the same time compatible with some automated liquid handling systems. Approximate dimensions: 15.0 cm x 10.6 cm x 2.2 cm. Approximate well size: 1.7 cm x 1.6 cm. Typical well volume: 500 to 1,000 µl. Well capacity: 3.5 ml.

CAT NO NAME DESCRIPTION
HR3-172 VDX邃「 Plate with sealant 24 plate case
HR3-170 VDX邃「 Plate with sealant 100 plate case

Hampton 蛋白质结晶试剂和耗材介绍

特色

Hampton 蛋白质结晶试剂和耗材介绍

美国Hampton Research公司位于加利福尼亚州,是一家专门从事蛋白质晶体研究的生产商。该公司向全球科研人员提供全面的晶体研究试剂和相关实验耗材,同时提供晶体设计和合成方面的定制服务。Hampton Research公司以其先进的生物大分子结晶技术和广泛实用的产品线,不仅为全世界晶体研究人员的工作带来了便捷,而且也受益于科研人员的回馈不断发展自己,目前已成为晶体研究领域最受信赖的品牌之一。
上海金畔生物作为Hampton research品牌蛋白结晶产品的代理商,我们将竭诚为您服务,欢迎新老客户咨询。

Hampton research主要产品:

产品分类 特点描述
Crystallization Screens 用于筛选和优化蛋白质/多肽/核酸结晶的一系列经验证的高精配方型溶液
Optimize Reagents 结晶级别盐类,聚合物,有机溶液或缓冲液
Crystallization Plates, Hardware & Accessories 结晶板(悬滴法和坐滴法,微量透析,微配液,自由界面扩散,凝胶以及无容器悬浮法)及其他配件
Cryocrystallography 低温晶体学耗材如Crystalcap system,cryoloops
Goniometer Heads&Supplies 测角器头和配件
Protein Crystallization Standards 结晶级别标准蛋白
Custom Shop
Crystallization Reagents
定制试剂盒和结晶溶液内的单一组分
StockOptions Kits 内含盐类,缓冲液和冷冻液的简便型试剂盒
Tools,Seeding&Resin 结晶用探针,结晶笔,seeding法结晶工具
Capillary Mounts & Supplies 毛细管,玻璃纤维, 蜡,黏合剂和密封剂

美国Hampton Research公司是世界上著名的蛋白质晶体试剂供应商,该公司的产品目录是由上海金畔生物科技有限公司提供,该目录分为12个大类和几十个小类。

Hampton蛋白质结晶试剂及耗材分类

第一类:Crystallization Screens   用于筛选和优化蛋白质/多肽/核酸结晶的一系列经验证的高精配方型溶液

1.PCT Pre-Crystallization Test(PCT预结晶试验)
应用:结晶筛选,确定相应的样品浓度,PCT试验用来预结晶结晶筛选,以确定适当的蛋白质浓度

  1. Slice pH(PH切片)

应用:溶解度和结晶筛选

  1. Solubility & Stability Screen(溶解度和稳定性的屏幕)

应用:溶解性和稳定性屏幕的设计,以协助识别解决方案的条件,促进蛋白质的溶解性和稳定性,并尽量减少蛋白质沉淀。

  1. Index

应用:不同的试剂系统的结晶屏幕的蛋白质复合物,多肽,核酸,水溶性小分子。

  1. Crystal Screen(晶体屏幕)

应用:
主屏幕的可溶性肽,蛋白质,核酸,和水溶性小分子。稀疏矩阵的加法屏幕
5.PEG/Ion Screen & PEG/Ion HT Screen 用于可溶性蛋白的结晶
6.PEG/Ion 2 Screen?用于可溶性生物大分子结晶
7.Crystal Screen? & Crystal Screen? HT 用于蛋白质,复合物,缩氨酸,核酸以及水溶性小分子的传统的经典结晶试剂
8.Crystal Screen 2?用于蛋白质,缩氨酸,核酸以及水溶性小分子的结晶
9.Crystal Screen Lite?用于蛋白质,缩氨酸和核酸的结晶试剂
10.Crystal Screen Cryo?用于蛋白质,缩氨酸,核酸的结晶
11.Grid ScreenTM用于蛋白质的结晶,分为七小类。
12.Quik Screen?用于可溶性蛋白的结晶
13.Quik Optimize?快速优化试剂,与Quik Screen? 或 custom screen配套使用
14.Low Ionic Strength Screen?用于完整的单克隆抗体,单克隆抗体片段以及低离子浓度很少溶解的蛋白的结晶
15.Nucleic Acid Mini Screen?用于核酸片段的结晶化
16.Natrix?用于核酸,蛋白核酸聚合物的结晶
17.MembFac?& MembFac? HT用于膜蛋白的结晶
18.Additive Screen?增强或改变样品可溶性的试剂
19.Detergent Screen?去垢剂
20.Heavy Atom Screens重原子结晶试剂
21.Izit Crystal Dye?蛋白染色试剂,用于区分蛋白晶体和盐晶体

第二类:Custom Shop Crystallization Reagents  结晶试剂盒中单独的试剂

  1. Solubility & Stability Individual Reagents
  2. Slice pH Individual Reagents
  3. Ionic Liquid Screen Individual Reagents
  4. Proti-Ace & Proti-Ace 2 Individual Reagents
  5. PCT Individual Reagents
  6. Silver Bullets & Silver Bullets HT Individual Reagents
  7. Silver Bullets Bio & Silver Bullets Bio HT Individual Reagents
  8. Index • Index HT Individual Reagents
  9. PEGRx 1 Individual Reagents
  10. PEGRx 2 Individual Reagents
  11. SaltRx Individual Reagents
  12. PEG/Ion Individual Reagents
  13. Crystal Screen Lite Individual Reagents
  14. Crystal Screen Cryo Individual Reagents
  15. Crystal Screen 2 Cryo Individual Reagents
  16. Grid Screen Ammonium Sulfate Individual Reagents
  17. Grid Screen PEG 6000 Individual Reagent
  18. Grid Screen Sodium Chloride Individual Reagents
  19. Grid Screen PEG/LiCl Individual Reagents
  20. Quik Screen Individual Reagents
  21. Natrix Individual Reagents

第三类:Optimize Reagents 优化试剂

1.Optimize-Polymers聚合体
2.Optimize-Organics (Volatile) 挥发性有机物
3.Optimize-Organics (Non-Volatile)非挥发性的有机物
4.Optimize-Salts 盐类
5.Optimize-Buffers缓冲液
6.Optimize-Solubilizing Agents (NDSB) 溶解试剂NDSB
7.Optimize-Reducing Agent还原剂-TCEP氢氯化物
8.Optimize-Cryoprotectants
9.Optimize-Oils用于结晶的油类
10.Optimize-Silica Hydrogel硅胶
11.Optimize-LM Agarose低熔点琼脂糖

第四类:StockOptions Kits

  1. StockOptions Salt
  2. StockOptions pH
  3. StockOptions Buffer
  4. CryoPro

第五类:Crystallization Plates, Hardware & Accessories 结晶耗材

1.24 Well Crystallization Plates 24孔晶体板-分悬滴和坐滴两种
2.48 Well Crystallization Plates 48孔晶体板
3.72 Well Crystallization Plates72孔晶体板
4.96 Well Crystallization Plates 96孔晶体板
5.384 Well Crystallization Plates 384孔晶体板-用于坐滴的结晶
6.Cover Slides & Related Tools
7.Glass Sitting Drop Rods用于坐滴的结晶
8.Micro-Bridges?微桥-坐滴结晶的支撑物
9.Glass Plates – 3 and 9 Well3孔和9孔玻璃板
10.Sealants, Sealing Grease, Oils, Applicator密封油脂,油及其它器具
11.Sealing Films, Tapes, Mats & Covers
12.Microdialysis Buttons, Rods & Membranes微量渗析结晶化
13.Granada Crystallization Box

第六类:Tools, Seeding & Resin(结晶工具、树脂)

  1. Tungsten-carbide Glass Cutter
  2. X-Acto Gripster Knife
  3. Micro-Tools™ Set
  4. Micro-Tools II™ Set
  5. Forceps
  6. Crystal Probe™
  7. Crystal Pencil
  8. Seed Bead
  9. Seeding Tool

第七类:Cryocrystallography

  1. CrystalCap HT™ Systems
  2. CrystalCap Magnetic™ Systems
  3. CrystalCap™ Systems
  4. CryoLoops & MicroTubes
  5. Cryo Tools
  6. Canes, Sleeves, Coders & Boxes
  7. Dewars

第八类:Capillary Mounts & Supplies(毛细管座椅支架供应)
第九类:Goniometer Heads & Supplies(测角头及用品)
第十类:Xenon Derivatization(氙气衍生物)
第十一类:Labels & Pens(标签和记录笔)
第十二类:Protein Crystallization Standards(蛋白质结晶的标准)
Hampton代理,Hampton上海代理,Hampton北京代理,Hampton广州代理,Hampton总代理,Hampton一级代理,Hampton特约代理,Hampton现货上海金畔生物科技有限公司Hampton专业代理。
Sigma代理  Abcam代理  CST代理  Santa Cruz代理  Biolegend代理 ebioscience代理  Invitrogen代理   millipore代理  BD流式抗体代理   GeneTe x抗体代理  Novus抗体代理   R&D代理 Biovison代理  Jackson代理  MBL抗体代理  ProSpec抗体代理  Bethyl抗体代理  Antibody Revolution抗体代理  Torrey Pines Biolabs代理  Amresco代理  MPbio代理  Laysan bio代理  NANOCS代理  Avanti代理  wako代理  lumiprobe代理(活性荧光染料)   NEB酶代理  Roche酶代理  Toyobo酶代理   USP代理  EP代理  Dr代理  TRC代理  TCI代理  Reagecon代理 Megazyme代理 Hampton代理(蛋白结晶) whatman代理(滤膜滤纸) GE代理(蛋白纯化) Corning康宁代理  Axygen代理 Falcon代理  NISSUI日水代理 Himedia代理 OXOID代理  BD培养基代理 Ludger代理(糖蛋白分析产品)  Eppendorf代理  Labnet代理  标准品代理 抗体代理 酶试剂代理  培养基代理 耗材代理 Elisa试剂盒代理 。

Hampton GRAS 1 • GRAS 2 Screens

Hampton GRAS 1 • GRAS 2 Screens

stallization screen for proteins, including monoclonal antibodies, where Polyethylene glycol is the primary, and Salt the secondary reagent, sampling pH 4-9
GRAS 1 • GRAS 2 ScreensGRAS 1 • GRAS 2 Screens Identify GRAS based reagents that promote crystallization of biotherapeutics for bioprocess, bioformulation, and continuous flow manufacturing applications
Features

Developed at Hampton Research
Generally Recognized As Safe reagent formulation
Samples pH 4.0 – 9.0 without an added buffer
Primary crystallization reagent:

GRAS Screen 1: PEG 300, 400, MME 550, & 600
GRAS Screen 2: PEG 1,000, MME 2,000, 3,350 & 4,000
Secondary crystallization reagent:

24 unique salts
Compatible with Vapor diffusion, microbatch, free interface diffusion
Reagents soluble between 4°C and 30°C

Description
GRAS Screen™ 1 and GRAS Screen™ 2 were developed by Hampton Research for the crystallization of proteins, including monoclonal antibodies. Each of the chemicals in GRAS Screen 1 and 2 have been used under one or more of the following categories. As (1) a Generally Recognized As Safe (GRAS) substance, (2) a pharmaceutical excipient, (3) a normal physiological constituent, (4) a metabolic byproduct, and/or (5) a Everything Added to Food in the United States (EAFUS) substance.
GRAS Screen 1 samples four low molecular weight Polyethylene glycols (300, 400, MME 550, and 600) versus twenty-four salts, encompassing pH 4-9. GRAS Screen 1 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 1 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.
GRAS Screen 2 samples four medium molecular weight Polyethylene glycols (1,000, MME 2,000, 3,350, & 4,000) versus twenty-four salts, encompassing pH 4-9. GRAS Screen 2 is supplied in a 96 Deep Well block format and is compatible with robotic and multi-channel pipet liquid handling systems. GRAS Screen 2 is compatible with vapor diffusion, free interface diffusion, and microbatch crystallization methods. For research use only.

CAT NO NAME DESCRIPTION
HR2-451 GRAS Screen 1 1 ml, Deep Well block format
Price Quantity
$245.00
CAT NO NAME DESCRIPTION
HR2-452 GRAS Screen 2 1 ml, Deep Well block format
Price Quantity
$245.00

低温泡沫杜瓦瓶 Spearlab Cryogenic Foam Dewars

低温泡沫杜瓦瓶 Spearlab Cryogenic Foam Dewars
Spearlab Cryogenic Foam Dewars
Spearlab Dewars
Spearlab Cryogenic Foam Dewars
HR4-662 Cryogenic Foam Dewar (500 ml) – Small  500ml规格
Spearlab Cryogenic Foam Dewars
HR4-675 – Spearlab Cryogenic Foam Dewar (2 liter)  2L规格
低温泡沫杜瓦瓶 Spearlab Cryogenic Foam Dewars
Applications 应用
    Cryocrystallography 蛋白结晶学

Features
  Each dewar is supplied with a lid  每个杜瓦瓶都配有盖子
  Proprietary foam construction (USPTO # 7,971,744)
  Mini (130 ml), Small (500 ml), Standard (800 ml), Large (1400 ml) and Tall (1800 ml)
   Reduced ice formation on dewar lip
  Easier to dry
   Foam construction reduces slipping

Description
Spearlab FD-130 Cryogenic Foam Dewar (130 ml) – Mini : Small, hexagonal outside, hand held foam dewar, maximum volume 175 ml. Each dewar is supplied with a matching foam lid to insulate the contents from ambient air. Dimensions of the cylindrical cavity in this vessel are 2 inches in diameter by 3.5 inches deep, so that it easily holds 130 ml and a maximum volume of 175 ml of liquid nitrogen. The HR4-676 has an overall height of approximately 4.5 inches without cover and the width is 3.5 inches at the top and 3.75 inches on the bottom (measured on the flats of the hexagon). Circular cover is approximately 0.5 inches tall x 3.5 inches diameter.
Spearlab Cryogenic Foam Dewar (500 ml) – Small: The small foam dewar shape is circular, with a protruding handle, so that it resembles a large teardrop. Each dewar is supplied with a matching foam lid to insulate the contents from ambient air. Dimensions of the cylindrical cavity in this vessel are 4.5 inches in diameter by 2.8 inches deep, so that it easily holds 500 ml of liquid nitrogen.
Spearlab FD-800 Cryogenic Foam Dewar (800 ml) – Standard: The standard foam dewar shape is circular, with a protruding handle, so that it resembles a large teardrop. Each dewar is supplied with a matching foam lid to insulate the contents from ambient air. Dimensions of the cylindrical cavity in this vessel are 5.8 inches in diameter by 2.8 inches deep, so that it easily holds 800 ml of liquid nitrogen.
Spearlab FD-1400 Cryogenic Foam Dewar (1400 ml) – Large: The large foam dewar shape is circular, with a protruding handle, so that it resembles a large teardrop. Each dewar is supplied with a matching foam lid to insulate the contents from ambient air. Dimensions of the cylindrical cavity in this vessel are 6.3 inches in diameter by 3.8 inches deep, so that it easily holds 1400 ml of liquid nitrogen. Overall height is approximately 6 inches without cover and the width is 9 inches on the short axis and 11 inches on the long axis. Cover approximately 0.5 inches tall x 9 inches diameter.
Spearlab FD-1800 Cryogenic Foam Dewar (1800 ml) – Tall: The tall foam dewar shape is a tapered octagon on the outside with a cylindrical interior. The tapered octagon features a wide, stable base. Each dewar is supplied with a matching foam lid to insulate the contents from ambient air. Dimensions of the cylindrical cavity in this vessel are 3.5 inches in diameter by 12.5 inches deep, so that it holds approximately 1,800 ml of liquid nitrogen. The outside dimensions of the tall dewar are 15.25 inches tall with a 6.25 inches wide top and a 7.75 inches wide base (measured on the flats of the octagon). The cover is 6.5 inches in diameter and 0.5 inches thick.
The patented (USPTO # 7,971,744) design of the Spearlab Cryogenic Foam Dewar makes it easy to handle and safer to use than a traditional low profile glass dewar. Also, because of its lower thermal mass, a foam vessel will cause less boil off when it is filled with liquid nitrogen. Additionally, the dewar will accumulate less frost during regular use. The end result is that less liquid nitrogen is consumed.
The dewars are made from cross-linked polyethylene foam. A density of 4 pounds per cubic foot is used for the 130 ml and 800 ml dewars. A density of 2 pounds per foot is used for the 1400 ml and 2 liter dewars. The higher density foam has significantly higher mechanical strength and stiffness. The lower density foam has slightly lower thermal conductivity. Like most lightweight insulation materials, the thermal conductivity of the foam is predominantly determined by the thermal conductivity of air, which eventually permeates the pores of the foam material.

CAT NO NAME DESCRIPTION
HR4-676 Cryogenic Foam Dewar (130 ml) – Mini each
HR4-662 Cryogenic Foam Dewar (500 ml) – Small each
HR4-673 Cryogenic Foam Dewar (800 ml) – Standard each
HR4-674 Cryogenic Foam Dewar (1400 ml) – Large each
HR4-675 Cryogenic Foam Dewar (2 liter) – Tall each

Hampton 96孔坐滴蛋白结晶板–Intelli-Plate

Hampton 96孔坐滴蛋白结晶板–Intelli-Plate
在生命科学领域,上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。庆祝上海金畔生物正式成为Hampton Intelli-Plate 96孔蛋白结晶板的签约代理商,在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱,我们将一如既往的为广大客户带来Hampton Intelli-Plate 96孔蛋白结晶板高品质的产品和服务,欢迎广大新老客户来电咨询。
Intelli-Plate 96 (Art Robbins Instruments)
Applications
  Sitting Drop Crystallization   用于蛋白坐滴结晶
Features  特征:

SBS microplate footprint & standard well spacing
Optically clear wells provide for superior crystal imaging
Well layout makes crystal harvesting easier
UV transmissible and low birefringence
2 well versions available in small and large drop well or two identical shallow drop wells
3 well versions are ideal for optimizing protein concentration, additive screens, drop ratio and combinatorial experiments
Rounded reservoir corners to prevent reservoir (MPD) creep

Description
Art Robbins Instruments has developed the ideal family of plates for crystallography applications: the Intelli-Plate. All versions of the Intelli-Plate have the SBS microplate footprint and standard well spacing and are ideal for manual or automated processing.
The Intelli-Plate 96-2 Low Profile (Art Robbins 102-0001-10 Hampton Research HR3-116 and HR3-117) is a low profile version of the Intelli-Plate 96-2 LVR (Low Volume Reservoir). Reservoir volume: 100 µl max. Drop well volume: 4 µl and 10 µl max. UV transmissible and low birefringence.
The CrystalMation Intelli-Plate 96-3 low-profile crystallization plate (Art Robbins 102-0001-13 Hampton Research HR3-118 and HR3-119) is a low profile version of the Intelli-Plate 96-3 LVR (Low Volume Reservoir). The plate is designed for sitting drop vapor diffusion crystallization experiments. It is constructed from optically clear, UV-transmissible, chemically resistant plastic with superior low birefringence. The low-profile construction allows for higher density in plate storage and imaging systems, maximizing your investment and valuable space. The plate is designed to be a substantial improvement in existing low-profile plates, allowing for superior sealing due to thicker well design and a flat sealing surface. It has been built to the SBS (Society for Biomolecular Screening) standard dimensions with 8 vertical wells along the left side of the plate (A-H) and 12 horizontal wells along the top of the plate (1-12). It is compatible with automated instrumentation including the CrystalMation line of instruments from Rigaku. The plate features three identical sized sample drop wells per reservoir. The wells are concave depressions along the left side (Y-axis) of the plate and are located on the ledge above the adjacent, flat bottom reagent reservoir. Each well features a round bottom for easy crystal harvesting and can hold up to 1 µl of sample. The multiple well design allows for combinatorial experiments, complex co-crystallization experiments for ligand screening, or for drop concentration variation. The reagent reservoir is typically filled with 50 to 70 µl of reagent. Reservoir volume: 100 µl max. Drop well volume: 1 µl max. UV transmissible and low birefringence.
The Intelli-Plate 96-2 LVR (Art Robbins 102-0001-00 Hampton Research HR3-143 and HR3-145) is a Low Volume Reservoir version of the original Intelli-Plate. Reservoir volume: 100 µl max. Drop well volume: 1 µl max. UV transmissible and low birefringence.
The Intelli-Plate 96-3 LVR (Art Robbins 102-0001-03 Hampton Research HR3-183 and HR3-185) is a Low Volume Reservoir, 3 drop well version of the Intelli-Plate. Reservoir volume: 100 µl max. Typical reservoir volume 50 µl. Drop well volume: 1 µl max. UV transmissible and low birefringence.
The Intelli-Plate 96-2 Original crystallization plate (Art Robbins 102-0011-00 Hampton Research HR3-297 and HR3-299) is an optically clear plate for sitting drop vapor diffusion crystallization. All wells have standard 9 mm spacing to conform to SBS standards with 8 vertical wells along the left side of the plate (A-H) and 12 horizontal wells along the top of the plate (1-12). This plate features two locations for sample per reservoir. The sample drop locations are located along the left side of the reagent reservoir, along the Y-axis of the plate. The sample wells are concave depressions on the ledge above the adjacent, flat bottom reagent reservoir. One sample well is located above the second sample well. The top sample well can hold 10 µl or less of sample. The lower sample well can hold 4 µl or less of sample. The reagent reservoir is typically filled with 100 µl of reagent and is capable of holding up to 300 µl of reagent. The sidewalls separating adjacent wells or reservoirs are 0.9 and 1.0 mm thick in order to offer a larger area for sealing the plate and a separation of the reservoirs. This plate is rigid, with virtually no torsional flex and is designed for either manual or automated pipetting. UV transmissible and low birefringence.
The Intelli-Plate Flat Shelf (Art Robbins 102-0001-01 Hampton Research HR8-171 and HR8-172) crystallization plate is a flat drop shelf version of the original Intelli-Plate. Reservoir volume: 300 µl max. No drop well. UV transmissible and low birefringence.
The Intelli-Plate 96-2 Shallow Well (Art Robbins 102-0001-20 Hampton Research HR3-163 and HR3-164) has two identically sized 2 µL reaction wells and a 140 µL screen reservoir. Each of the two identical well features a round bottom shallow well design for easy crystal harvesting and is arranged in an 8 x 12 array. This plate has low birefringence and is UV compatible. This plate is also available in a low profile height (Art Robbins 102-0001-21).
The plates can be sealed using Crystal Clear Sealing Film (HR3-609), 3 inch wide Crystal Clear Sealing Tape (HR4-506) or ClearSeal Film™ (HR4-521).
The height of Intelli-Plate is 0.560 inches. The height of Intelli-Plate Low Profile is 0.315 inches (8.001 mm).
Intelli-Plate 96 (Art Robbins Instruments)
Intelli-Plate 96-3

CAT NO NAME DESCRIPTION
HR3-116 Intelli-Plate 96-2 Low Profile 20 plate case
HR3-117 Intelli-Plate 96-2 Low Profile 80 plate case
HR3-118 CrystalMation Intelli-Plate 96-3 low-profile 20 plate case
HR3-119 CrystalMation Intelli-Plate 96-3 low-profile 80 plate case
HR3-143 Intelli-Plate 96-2 LVR 10 plate case
HR3-145 Intelli-Plate 96-2 LVR 40 plate case
HR3-183 Intelli-Plate 96-3 LVR 10 plate case
HR3-185 Intelli-Plate 96-3 LVR 40 plate case
HR3-297 Intelli-Plate 96-2 Original 10 plate case
HR3-299 Intelli-Plate 96-2 Original 40 plate case
HR8-171 Intelli-Plate Flat Shelf 10 plate case
HR8-172 Intelli-Plate Flat Shelf 40 plate case
HR3-163 Intelli-Plate 96-2 Shallow Well 10 plate case
HR3-164 Intelli-Plate 96-2 Shallow Well 40 plate case
HR3-181 Intelli-Plate 96-2 Shallow Well Low Profile 20 plate case
HR3-182 Intelli-Plate 96-2 Shallow Well Low Profile 80 plate case

Sigma代理  Abcam代理  CST代理  Santa Cruz代理  Biolegend代理 ebioscience代理  Invitrogen代理   millipore代理  BD流式抗体代理   GeneTe x抗体代理  Novus抗体代理   R&D代理 Biovison代理  Jackson代理  MBL抗体代理  ProSpec抗体代理  Bethyl抗体代理  Antibody Revolution抗体代理  Torrey Pines Biolabs代理  Amresco代理  MPbio代理  Laysan bio代理  NANOCS代理  Avanti代理  wako代理  lumiprobe代理(活性荧光染料)   NEB酶代理  Roche酶代理  Toyobo酶代理   USP代理  EP代理  Dr代理  TRC代理  TCI代理  Reagecon代理 Megazyme代理 Hampton代理(蛋白结晶) whatman代理(滤膜滤纸) GE代理(蛋白纯化) Corning康宁代理  Axygen代理 Falcon代理  NISSUI日水代理 Himedia代理 OXOID代理  BD培养基代理 Ludger代理(糖蛋白分析产品)  Eppendorf代理  Labnet代理  标准品代理 抗体代理 酶试剂代理  培养基代理 耗材代理 Elisa试剂盒代理 。

Hampton 银弹 Silver Bullets

Hampton 银弹 Silver Bullets

Applications

Additive screen for the optimization of protein crystals
For use with soluble proteins and membrane proteins
Additive screen to discover different crystal forms
Secondary or orthogonal crystallization screen when traditional screens are not successful
Additive screen for the optimization of protein solubility and stability
Features

Developed at Hampton Research
Screens a portfolio of small molecules and excipients for their ability to establish stabilizing, intermolecular, hydrogen bonding, hydrophobic and electrostatic interactions which could promote lattice formation and crystallization

Small organic acids & organic salts
Biologically active small molecules
Amino acids & peptides
Macromolecular digests
Co-factors & ligands
Biochemical pathway intermediates
Nucleotides, pharmacaphores & carbohydrates

Description
Silver Bullets screens a portfolio of small molecules for their ability to establish stabilizing, inter molecular, hydrogen bonding, hydrophobic and electrostatic interactions which could promote stability, lattice formation, and crystallization.1-3
Published results with the Silver Bullets have been very encouraging, with more than twice as many proteins being crystallized overall as were crystallized from controls free of any small molecules.1-3
X-ray diffraction analysis has revealed the small molecule Silver Bullets in the crystal lattice, involved at the centers of hydrogen bonding networks and electrostatic interaction.1-3 Silver Bullets is compatible with hanging, sitting and sandwich drop vapor diffusion, microbatch, free interface, and microdialysis crystallization methods. Silver Bullets can be used with Dynamic Light Scattering (DLS), ThermoFluor, and Size Exclusion Chromatography assays.
Silver Bullets reagent portfolio
•Organic salts and acids
•Biologically active small molecules
•Amino acids and peptides
•Macromolecular digests
The Silver Bullets kit is a library of small molecules that have been shown to promote crystal lattice formation. X-ray diffraction analysis has demonstrated the reagents have the ability to:
•Stabilize the conformation of the protein
•Perturb the interaction of the protein with the solvent
•Participate in forming important lattice contacts
•Build the crystal lattice by forming reversible cross-links between the macromolecules in the crystal
The Silver Bullets kit is composed of 96 solutions in a single Deep Well block (Greiner 786261 block specifications: Total Volume: 0.5 mL Working Volume: 0.03 – 0.7 mL at Room Temperature 0.03 – 0.55 mL at -20ºC, Well Profile: Conical (V), Bottom Well Bottom: Solid, Plate Color: Translucent), HT format.
Each Silver Bullets reagent is a mixture of small molecules or macromolecular digests in 0.02 M HEPES sodium pH 6.8 buffer. Each solution contains between 2 and 20 small molecules.
Silver Bullets reagent volume is 0.5 ml (each well).
ThermoFluor is a registered trademark of Johnson & Johnson.

Hampton  Silver Bullets Bio

Silver Bullets • Silver Bullets Bio
Silver Bullets • Silver Bullets Bio
上海金畔生物作为Hampton蛋白结晶产品的代理商,竭诚为您服务,欢迎新老客户咨询。
Applications 应用

Additive screen for the optimization of protein crystals
For use with soluble proteins and membrane proteins
Additive screen to discover different crystal forms
Secondary or orthogonal crystallization screen when traditional screens are not successful
Additive screen for the optimization of protein solubility and stability

Features

Screens a portfolio of small molecules and excipients for their ability to establish stabilizing, intermolecular, hydrogen bonding, hydrophobic and electrostatic interactions which could promote lattice formation and crystallization

Small organic acids & organic salts
Biologically active small molecules
Amino acids & peptides
Macromolecular digests
Co-factors & ligands
Biochemical pathway intermediates
Nucleotides, pharmacaphores & carbohydrates

 

Developed at Hampton Research
Two sets of 96 reagents, composed of more than 1,090 chemicals, of which more than 400 are uniqu

Please note, the Silver Bullets Bio Screen is temporarily unavailable as a new formulation is in development
 

Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate

Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate
美国Hampton Research公司位于加利福尼亚州,是一家专门从事蛋白质晶体研究的生产商。该公司向全球科研人员提供全面的晶体研究试剂和相关实验耗材,同时提供晶体设计和合成方面的定制服务。Hampton Research公司以其先进的生物大分子结晶技术和广泛实用的产品线,不仅为全世界晶体研究人员的工作带来了便捷,而且也受益于科研人员的回馈不断发展自己,目前已成为晶体研究领域最受信赖的品牌之一。
Hampton research主要产品:
Crystallization Screens 用于筛选和优化蛋白质/多肽/核酸结晶的一系列经验证的高精配方型溶液
Optimize Reagents 结晶级别盐类,聚合物,有机溶液或缓冲液
Crystallization Plates, Hardware & Accessories 结晶板(悬滴法和坐滴法,微量透析,微配液,自由界面扩散,凝胶以及无容器悬浮法)及其他配件
Cryocrystallography 低温晶体学耗材如 Crystalcap system,cryoloops
Goniometer Heads&Supplies 测角器头和配件
Protein Crystallization Standards 结晶级别标准蛋白
Custom Shop Crystallization Reagents 定制试剂盒和结晶溶液内的单一组分
StockOptions Kits 内含盐类,缓冲液和冷冻液的简便型试剂盒
Tools,Seeding&Resin 结晶用探针,结晶笔,seeding法结晶工具
Capillary Mounts & Supplies 毛细管,玻璃纤维, 蜡,黏合剂和密封剂
Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate
HDP Hanging Drop Crystallization Plate (Swissci)
HDP Hanging Drop Plate
HDP Hanging Drop Crystallization Plate (Swissci)
Single Well with Tool
HDP Hanging Drop Crystallization Plate (Swissci)
Hanging Drop Wells
Applications—Hanging drop crystallization
Features
  Made from optically superior polymer (UVP)
  Allen key novel crystal plug closure system
  Wells are micro-numbered
Description  描述:
The Swissci Hanging Drop Crystallization Plate is a breakthrough for protein crystallization in a 96-well format. For the first time individual wells can be identified and removed without any disturbance to the growing crystals inside the plate.Description
The plate has been developed by Swissci AG together with leading Crystallographers. It is the result of many years of experience in successful robotic high-throughput crystallization.
The Hanging Drop Crystallization Plate offers unique properties that make it ideal for both nanoliter crystallization screening and microliter optimization alike. Made from optically superior polymer (UVP) and with a new design of the wells, the plate allows easy crystal viewing and retrieval. The system is fully covered by design and patent protection.
The Advantages of the Hanging Drop Crystallization Plate
Easy Crystal Retrieval
Raised wide wells make the crystal mounting especially easy. Allen key system allows for smooth removal and subsequent microscopic investigation / X-ray with the novel crystal plug closure all included in the system.
Easy Viewing
The wells are wide conical and have a lens effect for perfect illumination. The micro-numbering ensures you will never loose the location under the microscope.
The optically superior polymer is UV transmissible and can be used to differentiate between salt and protein crystals.
Integral Sealing
Wide partition walls between each well provides a high surface area for very good sealing with the advanced quality sealing tape. The sealing tape is integrated into the kit so there is no need to purchase additional parts prior to starting a procedure.
Wide Range of Volumes
Typical volumes are 50 – 200 µl of reservoir and 10 nanoliter – 5 microliter drop size.
SBS Standard
The complete plate is designed to the 96-well SBS standard for all common holders.

CAT NO NAME DESCRIPTION
HR3-187 Hanging Drop Crystallization Plate (Swissci) 10 plate case

Hampton蛋白悬滴结晶板 HDP Hanging Drop Crystallization Plate 相关产品:

96 Well Hanging Drop Vapor Diffusion Plate
Hanging drop crystallization
ARI Hanging Drop Seals for 96 Well Plates
ARI Hanging Drop Seals for 96 Well Plates
CrystalQuick 96 Well Sitting Drop Plate (Greiner)
Sitting drop crystallization
Detergent Screen HT
96 detergents Deep Well block format
Glass Cover Slide Gizmo Dispenser
Cover Slide Dispenser
Greiner ComboPlate and CrystalBridge
Hanging and sitting drop crystallization
HDP Hanging Drop Crystallization Plate (Swissci)
Hanging Drop Crystallization
Linbro Plate
Hanging drop crystallization
ProCrystal
Protein Crystallization Covers for Hanging Drop Vapor Diffusion
Protein Methods
Daniel M. Bollag, Michael D. Rozycki, & Stuart J. Edelstein
Solubility & Stability Screen
Identify protein specific additives that promote solubility and stability
UVP Hanging Drop Plate Seal (Swissci)
Swissci UVP Hanging Drop Plate Seal
VDX Plate with sealant
Hanging drop crystallization
VDX Plate without sealant
Hanging drop crystallization
VDX48 Plate with sealant
Hanging drop crystallization
VDXm Plate without sealant
Hanging drop crystallization
VDXm Plate with sealant
Hanging drop crystallization

 

Hampton坐滴蛋白结晶板 3 Well Crystallization Plate (Swissci)

Hampton坐滴蛋白结晶板     3 Well Crystallization Plate (Swissci)
3 Well Crystallization Plate (Swissci)
Applications:Sitting drop crystallization  应用于坐滴结晶
该坐滴结晶板的特点:Features

Lens effect drop wells for enhanced optics
Drop volume: 50 nl to 5 碌l
Micro-numbering alongside drop volumes
Reservoir volume: 20 to 40 碌l
ANSI/SLAS 1-2004 Standard
Drop well allows easier crystal harvesting
Three drop wells per reservoir
Midi profile or Low Profile for easier storage
UV compatible (UVP)

Hampton坐滴蛋白结晶板3    Well Crystallization Plate (Swissci)
Description
The SWISSCI 3 Lens Crystallization Plate is an ideal product for protein crystallization presented in a 96-well plate format.
该结晶板是用于在96孔板呈现蛋白质结晶的理想产品
The plate was developed in collaboration with very experienced protein crystallographers. It is the result of many years of experience in successful robotic high-throughput crystallization and combines many of the necessary features not earlier available to the crystallographer.
该板协同经验非常丰富的蛋白质晶体学家开发。这是多年的成功的机器人高通量结晶经验的结果,并结合了许多不早提供给晶体学家必要的功能。
The SWISSCI 3 Lens crystallization Plate offers unique properties that make it ideal for both nanoliter crystallization screening and mircoliter optimization alike. Made from optically superior polymer (UVP) and with a new design of the wells, the plate allows easy crystal viewing and retrieval.The Advantages of the 3 Lens Crystallization Plate    优点:Easy crystal retrieval   易结晶
Raised wide wells make the crystal mounting especially easy.Easy viewing
The wells are a wide conical shape and have a lens effect for perfect illumination. The micro-numbering ensures you will never get lost again (visible by microscope). The optically superior polymer is UV transmissible and may be used to differentiate between salt and protein crystals.Better sealing
Wide partition walls between the wells give plenty of area for good sealing with tape. No central bending occurs in this very robust structure. Excellent long term storage – no sample evaporation.Wide range of volumes
Typical volumes are 20-40 µl of reservoir and 50 nl-5 µl drop size. The 288 optical wells offer three times the number of experimental constructions.ANSI/SLAS 1-2004 Standard
The plates are designed to the 96-well ANSI/SLAS 1-2004 standards for all common holders and external numbering (A-H, 1-12)with corner location make the plate easy to use in a robotic sampler. The 3 Lens plate is suitable for centrifugation. The unique 3 drop protein crystallization plate offers a new way of sitting-drop crystallography. The 288 wells are optically perfect designed to observe crystals under a microscope.3 Lens plate features
Easy to fill 96-lens structure – typically 30 microlitres per buffer lens. Standard ANSI/SLAS 1-2004 form for automation. Optically perfect wells with lens effect for a better view with microscope. Microscopic identifier within wells, simplifying the orientation under the microscope. Maximum volume of the buffer reservoir is 40 microlitres. Grown crystals are easy to identify and to remove from lens due to a low-binding polymer. Plate with 3 lenses for each sample, better growing security with triplicates or the ability to use lens two and lens three as mixing stations. Lenses fill without micro-droplets jumping out due to static effects. Wells can be individually sealed with a perfectly flat upper surface – there is a large land area designed to ensure integrity of each lens section. The profile allows for easier storage. Low volume buffer well enables savings on reagents. Triplicates allow for 288 constructs per plate.3 Well Midi Crystallization Plate (Swissci 3W96TUVP)
3 Well Low Profile Crystallization Plate (Swissci 3W96TLP-UVP)
Hampton坐滴蛋白结晶板  3 Well Crystallization Plate (Swissci)
Sitting drop crystallization

CAT NO NAME DESCRIPTION
HR3-123 3 Well Midi Crystallization Plate (Swissci) 10 plate case
HR3-125 3 Well Midi Crystallization Plate (Swissci) 40 plate case
HR3-205 3 Well Low Profile Crystallization Plate (Swissci) 10 plate case
HR3-206 3 Well Low Profile Crystallization Plate (Swissci) 40 plate case