日度归档：2024年11月1日

鹿genius®分子疫学分析POT配套元件（不动杆菌属菌用）|分子疫学分析POT套件|生化学试剂-基因工程|试剂|关东化学株式会社

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不动杆菌属菌，医疗环境，包括自然环境中广泛存在的机会感染细菌。另外，抗菌药耐药性不动杆菌属菌高度表现也包含监视，医疗相关感染的对策上重要。 名古屋大学的荒川先生及爱知县卫生研究所的铃木老师所开发的PCR -根据ORF Typing（POT法）中，多路聚合酶链反应，用不动杆菌属菌保有多数特定基因领域进行放大，琼脂糖凝胶电泳法而被分离的乐队模式的数值化，菌种简易鉴定及A . baumannii的菌株识别和国际流行克隆的识别。 *本试验法，厚生労働科学研究费补助金新兴·复兴对感染症的创新医药品等开发推进事业（H 24 -新兴-一般- 010）开发的东西。

特长

菌种简易鉴定（<em>A . baumannii</em>，<em>A . pittii</em>，<em>A . nosocomialis</em>，A . sp . close to 13 TU）可能

<em>A . baumannii</em>菌株能够识别

<em>A . baumannii</em>的国际流行克隆（微星科技cloneⅠ、Ⅱ）能够识别

Multilocus Sequence Typing（MLST）法和几乎同等的识别能力


配套元件的构成（30回）

个别名称 容量 数量
试剂A AptaTaq DNA主人（5×Conc .）* 240μL 一本书
试剂B PCR附录 240μL 一本书
试剂C 引物混合α 120μL 一本书
试剂D 混合β引物 120μL 一本书
试剂E 积极控制 240μL 一本书
试剂F 6×装入缓冲区（BPB·XC） 240μL 一本书
* AptaTaq DNA主人（5×Conc设置Roche Diagnostics K . K .的商品。

操作步骤

① 分离的菌株纯培养
② DNA抽出，进行模板DNA制备
③ 两种多路PCR
④ 琼脂糖凝胶电泳
⑤ 乐队的读取模式
差 POT值的计算
⑦ 各样品的POT值的比较分析
解析

鹿genius®分子疫学分析POT配套元件（不动杆菌属菌用）|分子疫学分析POT套件|生化学试剂-基因工程|试剂|关东化学株式会社

电泳模式

50 : 50个基点DNA梯形电脑：积极的控制1，2：A . baumannii（ST 2）同一事例得到的临床分离股票3：A . baumannii（ST 2）4：A . baumannii（ST 2）多药耐药性A . baumannii
5：A . baumannii（ST 1）ATCC®BAA 16056：A . baumannii（ST 1）7：A . baumannii（ST 152）8：A . baumannii（ST 34）9：A . pittii10：A . nosocomialis11：<em>A .</em>close to sp .A . nosocomialis

名古屋大学的荒川宜親老师和爱知县卫生研究所匡弘铃木老师的厚意，通过电泳模式的实例数据为您提供领受了。

检测ORF的种类（目标区域）及其PCR扩增产物尺寸

POT No . 放大尺寸（bp） 目标领域
Reactionmixture 1 PCR PC 553 atpA
A . baumannii 465 OXA – 51
A . pittii 401 Specific gene
A . nosocomialis 362 Specific gene
<em>A .</em> sp close TU to 13 . 321 Specific gene
POT 1 – 1 271 Genomic Islet – 1
POT 1 – 2 231 Genomic Islet – 2
POT 1 – 3 189 Genomic Islet – 3
POT 1 – 4 151 Genomic Islet – 4
POT 1 – 5 122 Genomic Islet – 5
POT 1 – 6 102 Genomic Islet – 6
POT 1 – 7 81 Genomic Islet – 7
Reactionmixture 2 PCR PC 565 OXA – 51
POT 2 – 1 457 Genomic Island – 1
POT 2 – 2 388 Genomic Island – 2
POT 2 – 3 329 Genomic Island – 3
POT 2 – 4 280 Genomic Island – 4
POT 2 – 5 237 Genomic Island – 5
POT 2 – 6 公元209 Genomic Island – 6
POT 3 – 1 185 Genomic Island – 7
POT 3 – 2 160 Genomic Island – 8
POT 3 – 3 139 Genomic Island – 9
POT 3 – 4 120 Genomic Island – 10
POT 3 – 5 101 Genomic Island – 11
POT 3 – 6 81 Genomic Island : 12

①2个多路PCR的电泳结果从乐队读取模式。 ②这电泳乐队的有无的结果用，POT值分析用EXCEL表二进法输入，3个类别的POT值计算出。 无论PCR电脑阳性的情况，那个样品已不动杆菌属菌，可以确认。 不论POT值1 1000以下的话A . baumannii，1000以上2000以下的话A . pittii，2000以上3000以下的话A . nosocomialis3000以上，4000以下的话A .close to 13 TU sp .，4000以上的话不动杆菌属菌的细菌种类不明，被判定。 在样品之间的POT值进行比较，A . baumannii菌体间的相同性客观的推测。 兴趣集体感染得菌身体，POT 1～3的POT值全部同一。

范畴 样品号码
1 2 3 4 5 6 7 8 9 10 11
POT 1 122 122 122 122 69 69 72 104 1105 2105 3105
POT 2 59 59 26 53 46 42 0 8 0 0 0
POT 3 54 54 54 41 59 27 8 0 0 0 0

产品信息

产品名 包装 产品编号
鹿genius®分子疫学分析POT配套元件（不动杆菌属菌用） 一包（30回） 08062 – 96
鹿genius®DNA抽出试剂 一包（120次） 08178 – 96

最新的价格是Cica – Web请参照。

书是爱知县套件★和名古屋大学专利许可，制造销售。★其他厂商的商品有关的许可证、专利方面，各厂商请确认。★产品规格，产品改良而变更。请您事先了承。

的相关产品

POT套件·PCR套件

产品名 包装 产品编号
鹿genius®分子疫学分析POT套件（黄色葡萄球菌用） 一包（30回） 08180 – 96
一包（120次） 08180 – 97
鹿genius®分子疫学分析POT配套元件（绿脓菌用） 一包（30回） 08187 – 96
鹿genius®分子疫学分析POT配套元件（大肠菌用） 一包（30回） 08362 – 97
鹿genius®ESBL基因型检测试剂盒 一包（30回） 08112 – 96
鹿genius®カルバペネマーゼ基因型检测试剂盒 一包（30回） 08114 – 96
鹿genius®致病基因检测试剂盒（PCR腹泻原性大肠菌用） 一包（100次） 08087 – 96
鹿genius®毒素基因检测试剂盒（C . difficile用） 一包（30回） 08115 – 96
鹿genius®コアグラーゼ检测套（黄色葡萄球菌用）
一包（50次） 08179 – 96

最新的价格是Cica – Web请参照。


分离培养基

产品名 包装 产品编号
黑藻アガーMDRA屏幕培养基 10张 72118

最新的价格是Cica – Web请参照。


电泳相关

产品名 包装 产品编号
琼脂糖KANTO A的酒馆熊猫聚会了 100克 01089 – 23
10×TBE缓冲液 一L 46510 : 79
溴化乙锭溶液（2毫克/毫升瓶装），眼药水 10毫升 14575 : 43
Quick‐Load Purple 50个基点DNA Ladder gel lanes 250 49914 : 40
6倍浓缩装入缓冲器 2 mL×6本 24080 – 96

最新的价格是Cica – Web请参照。

宣传手册、说明书（PDF）

小册子鹿genius®分子疫学解析配套元件（不动杆菌属菌用）（386 KB）

小册子鹿genius®POT套件系列（1.3 MB）

小册子鹿genius®基因检测试剂盒推荐组套（978 KB）设备

小册子基因检测相关产品指南（2.3 MB）

取扱说明书（598 KB）

计算表（ZIP文件，Excel）

POT值分析
用EXCEL表（ZIP文件，730 KB）

的相关产品

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信息查询

电话: 03 – 6214 – 1090

传真: 03 – 3241 – 1047

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Hampton PEG/Ion • PEG/Ion 2 • PEG/Ion HT

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Hampton PEG/Ion • PEG/Ion 2 • PEG/Ion HT

Applications
  Primary or secondary, polymer, salt and pH matrix crystallization screen for biological macromolecules
Features

Developed at Hampton Research
PEG/Ion is a sparse matrix profile of anions and cations in the presence of monodisperse Polyethylene glycol 3,350 over pH 4.5 – 9.2
PEG/Ion 2 screens a complete profile of titrated organic acids at varying pH levels (3.7 – 8.8) in the presence of monodisperse PEG 3,350
PEG/Ion HT combines PEG/Ion and PEG/Ion 2 in a single 96 Deep Well block
 Description

PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a primary crystallization reagent and in approximately 50% of those reports, the PEG was combined with an ion as a secondary crystallization reagent. PEG/Ion reagents are formulated without a buffer and are not pH titrated.
PEG/Ion 2 is an extension to the fundamental crystallization strategy in PEG/Ion. PEG/Ion 2 reagents cover the monodisperse, high purity Polyethylene glycol 3,350 and an array of neutralized and pH adjusted organic acids, multivalent ions, a novel Citrate BIS-TRIS propane buffer system and pH (4 – 8.8). The formulation of PEG/Ion 2 was developed at Hampton Research. Each of the 48 reagents in PEG/Ion 2 contains PEG 3,350 as the polymer (precipitant). The concentration of PEG is varied from 12% w/v to 20% w/v depending upon the type and concentration of buffer/salt paired with the polymer. Thirteen of the forty-eight PEG/Ion 2 reagents contain a separate buffer component. The remaining PEG/Ion 2 reagents are buffered by the titrated organic acid salt. Six of these thirteen conditions feature a novel Citric acid BIS-TRIS propane (CBTP) buffer. The CBTP buffer uses Citric acid and BIS-TRIS propane as the acid base pair to create a two component buffer system effective across pH 2.5 to 9.5. The ratio of Citric acid to BIS-TRIS propane determines the solution pH. Thirty-five of the forty-eight PEG/Ion 2 reagents contain a neutralized or pH adjusted organic acid in the presence of the polymer. Neutralized organic acids are highly effective crystallization salts.1 Four PEG/Ion 2 reagents feature polyvalent cations. Two of these reagents contain cation mixes, saving sample by screening six different cations with only two reagents. Tryptone, a casein digest combinatorial library of peptides, is included in PEG/Ion 2. PEG/Ion 2 reagents 1-30, 42, 45-47 are formulated without a buffer and are not pH titrated.
PEG/Ion contains 48 unique reagents, 10 ml each.
PEG/Ion 2 contains 48 unique reagents, 10 ml each.
PEG/Ion HT contains 1 ml of each reagent from PEG/Ion and PEG/Ion 2 in a single Deep Well block format.
Ready-to-use reagents are sterile filtered and formulated with ultra-pure Type 1 water, using the highest purity salts, polymers, organics and buffers. Individual reagents are available through the Hampton Research Custom Shop.
PEG/Ion • PEG/Ion 2 • PEG/Ion HT

PEG/Ion • PEG/Ion 2 • PEG/Ion HT
Crystals of Peptidoglycan Recognition Protein (PGRP) from camel milk grown using the Hampton Research PEG/Ion screen. Sharma, P., Singh, N., Sinha, M., Sharma, S., Perbandt, M., Betzel, C., Kaur, P., Srinivasan, A. & Singh, T.P. All India Institute of Medical Sciences, Department of Biophysics, New Delhi, India.

CAT NO NAME DESCRIPTION
HR2-126 PEG/Ion Screen 10 ml, tube format
HR2-098 PEG/Ion 2 Screen 10 ml, tube format
HR2-139 PEG/Ion HT 1 ml, Deep Well block format

Himedia Media for Anaerobes  厌氧菌培养基

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Himedia Media for Anaerobes  厌氧菌培养基
上海金畔生物科技有限公司，作为HiMedai公司在中国的代理商，在微生物培养和检测领域，会一如既往地为您带来优质的服务。
Himedia代理，欢迎新老客户访问Himedia官网或者咨询我们获取更多有关产品信息。
Veterinary > Media for Anaerobes

Media for anaerobes such as Clostridium spp. and others responsible for various diseases in veterinary animals are offered by HiMedia. Reinforced Clostridial Agar, SPS agar, Anaerobic Thioglycollate Medium Base are some of the medium used for their isolation and cultivation.
厌氧菌的培养基，如梭菌。其他对兽医疾病负责的人则由Himedia提供。强化梭菌琼脂、SPS琼脂、厌氧巯基培养基是分离和培养的几种培养基。
Himedia Media for Anaerobes  厌氧菌培养基

FD013 S.F.P. Supplement (Perfringens S.F.P. Supplement)
FD045 Egg Yolk Emulsion (50ml / 100 ml per vial)
GM154 Reinforced Clostridial Agar
GM632 SPS Agar
LQ080V Cooked Meat Broth
M1005 S.F.P. Agar Base
M149 Cooked M Medium (R.C.Medium)
M154 Reinforced Clostridial Agar
M1616 Anaerobic Thioglycollate Medium Base
M387 McClung Toabe Agar Base
M632 SPS Agar
M928 Liver Broth
MV1005 S.F.P. HiVeg™ Agar Base
MV154 Reinforced Clostridial HiVeg™ Agar
MV387 McClung Toabe HiVeg™ Agar Base
MV632 SPS HiVeg™ Agar

Harlan teklad官网动物饲料 Rabbit diets 兔饲料 国内高纤维兔饲料定制

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Harlan teklad官网动物饲料 Rabbit diets 兔饲料 全球高纤维兔饲料
特克勒德兔饲料是营养完整的颗粒饲料制定，以满足已知的营养需求兔在生长，繁殖和维持。
高质量的植物蛋白质来源提供了适当数量和比例的必需氨基酸，以促进家兔的一般健康和状况，在所有阶段的生命周期。
特克拉德兔日粮中含有脱水苜蓿粉，这是一种高品质的饲料成分，能促进消化系统的正常运转。紫花苜蓿粉中的蛋白质也被兔很好地利用。
矿物质和维生素强化这些饮食确保充足的营养平衡，以促进适当的生长，发育，维持和繁殖的研究兔。
产品
特克乐兔饲料 不可蒸压口罩 辐照
全兔饮食 2030，2030 C 2930
全球高纤维兔饲料 2031，2031 C 2931
15%兔饲料 8630
并不是所有的产品都是在当地库存的，可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时，一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存，可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点，人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲，当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月，有时甚至在生产后12个月。这种实践经验，随着时间的推移，再加上文献支持和维生素测试，让我们相信，这些饮食继续支持动物的健康和研究的完整性，至少在9个月后生产。如果你不确定当地的政策，请向你的机构寻求指导。
建议的储存条件：

  • 凉爽和干燥；在华氏70度或以下，湿度最好在50%以下，但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中，防止连续暴露于光线下，并将空气暴露在最小范围内。
兔子可能会被限制喂食，把一定数量的饲料放在鳄鱼或饲料斗一天一次。在维持和妊娠期限制喂养是一种有效的方法，以满足兔的营养需求，但它防止过多的体重增加。兔子也可以自食其力，把饲料放在料斗里，它们可以随意进食。该方法对兔生长、泌乳和幼仔繁殖最有效。
兔子的摄食要求会随品种、年龄和大小而变化。通过观察和控制喂养，可以保持适当的身体状况，以达到最大的性能。一只10磅重的新西兰白兔每天将消耗大约150克特克勒德兔的食物。

Teklad rabbit diets are nutritionally complete pelleted diets formulated to meet the known nutrient requirements of the rabbit during growth, reproduction and maintenance.
High-quality plant protein sources supply the proper amounts and proportions of essential amino acids necessary to promote the general health and condition of rabbits during all phases of the life cycle.
Teklad rabbit diets contain dehydrated alfalfa meal, a high-quality forage ingredient that promotes the proper functioning of the digestive system. The protein in alfalfa meal also is utilized well by rabbits.
Mineral and vitamin fortification of these diets ensures an adequate nutritional balance to promote the proper growth, development, maintenance, and reproduction of research rabbits.

Products
Teklad rabbit diets Non-autoclavable orm Irradiated
Teklad global rabbit diet 2030, 2030C 2930
Teklad global high fiber rabbit diet 2031, 2031C 2931
Teklad 15% rabbit diet 8630
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.
Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air
Rabbits may be limit-fed by placing a certain amount of feed in crocks or feeding hoppers once a day. Limit-feeding during maintenance and gestation is an efficient method of meeting the nutritional needs of the rabbit, yet it prevents excess weight gain. Rabbits also may be self-fed by placing feed in a hopper where they may eat at will. This method is most efficient for growing rabbits, lactating does, and young breeding stock.
Rabbit feeding requirements will vary with rabbit breed, age, and size. Through observation and controlled feeding, the proper body condition can be maintained for maximum performance. A ten-pound New Zealand white rabbit will consume approximately 150 g of Teklad rabbit diet per day.

Research Diets动物造模饲料Research diets 食源性肥胖症饲料    

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食源性肥胖症饲料    
Research Diets动物造模饲料Research diets 食源性肥胖症饲料
肥胖是一种世界范围内的慢性疾病，是导致高血压、糖尿病、冠心病、心肌梗死等多种慢性病发生的主要危险因。
 
遗传和环境因素对肥胖症的发生起重要作用，膳食则是影响肥胖症的主要的环境因素之一。膳食诱导的肥胖动物模型普遍被用于肥胖发生机理和治疗方法的研究。
 
我们与世界顶级动物饲料供应商美国RDI合作，为客户提供配方可报告、可复制、可修改的纯化饲料，我们的饲料具有造模时间短、造模效果好、有效易复制等特点。
 
重点推荐饲料：D12492和D12451。
 推荐产品  货号  规格  生产厂商
60%Kcal High-Fat(DIO) Diets D12492 12.5kg 美国RDI
45%Kcal High-Fat(DIO) Diets D12451 12.5kg 美国RDI
10%Kcal High-Fat(DIO) 7% Sucrose Control Diets match D12492 D12450J 12.5kg 美国RDI
10%Kcal High-Fat(DIO) 17% Sucrose Control Diets match D12451 D12450H 12.5kg 美国RDI
10%Kcal High-Fat(DIO) 35% Sucrose Control Diets D12450B 12.5kg 美国RDI
10%Kcal High-Fat(DIO) No Sucrose Control Diets D12450K 12.5kg 美国RDI
 糖尿病 / 胰岛素抵抗饲料    
精制的碳水化合物如高果糖玉米糖浆被用于许多加工的食品，美国的调查显示，自20世纪70年代开始，这种甜味剂的摄入量明显增加。
 
过去几十年我们认识到，过多的摄入这种精制的碳水化合物物与人体或动物模型中的体重增加、高脂血症和胰岛素抵抗相关。
在啮齿类动物中，高果糖饮食能够诱导SD大鼠、Wistar 大鼠和仓鼠高甘油三脂血症、胰岛素抵抗和高血压。
 
SD大鼠和Wistar大鼠是建立蔗糖诱导的胰岛素抵抗和高甘油三脂血症的很好模型。不同于大鼠和仓鼠，小鼠很少被用来建立胰岛素抵抗和高甘油三脂模型。
 
因为，常用的C57BL/6小鼠给予蔗糖/果糖饮食时，根本不形成胰岛素抵抗或者形成表型非常缓慢。
推荐饲料：D11707，D08040106。
 推荐产品  货号  规格  生产厂商
58%Kcal Diabetes/ Insulin Resistance Diets sucrose D12331 12.5kg 美国RDI
58%Kcal Diabetes/ Insulin Resistance Diets corn starch D12330 12.5kg 美国RDI
11%Kcal Diabetes/ Insulin Resistance Diets sucrose-Control D12329 12.5kg 美国RDI
11%Kcal Diabetes/ Insulin Resistance Diets corn starch-Control D12328 12.5kg 美国RDI
 脂肪肝（NAFLD）饲料    
非酒精性脂肪肝是一系列疾病状态，包括从脂肪变性到非酒精性脂肪性肝炎，其后进展为肝纤维化、肝硬化和肝癌。与人类很多疾病由膳食导致的一样，啮齿类动物的脂肪肝也可由膳食诱导。目前，常用三种膳食类型来诱导脂肪肝，分别为：蛋氨酸和胆碱缺乏（MCD）饲料、胆碱缺乏（CD）饲料和高脂（HFD）饲料。
 
MCD饲料用于研究肝病已有超过40年的历史，喂食MCD饲料的啮齿类动物将在2-4周内发展出显著脂肪肝，然后迅速演变为肝炎和纤维化。重要的是，与人类和其它方法诱导的NAFLD啮齿类动物模型不一样，喂养MCD饲料的啮齿类动物会减轻体重，且不发生胰岛素抵抗，这与人类典型的NASH患者情况相反，他们不但肥胖而且对胰岛素抵抗。
 
CD饲料与MCD饲料相比，潜在优势在于不但增加肝脏脂肪水平，而且增加体重，导致血脂异常和胰岛素抵抗。CD饲料所诱发的肝脏脂肪堆积、肝脏损伤和炎症并没有MCD饲料的严重。
 
HFD可以诱导啮齿类动物模型体重和体脂肪增加并导致胰岛素抵抗。一般来说，HFD喂养与MCD喂养相比，并不产生肝纤维化，且只有轻微脂肪肝。
 
推荐饲料：A02082002B，D05010401-03。
 推荐产品  货号  规格  生产厂商
Methionine and Choline Deficient Diet A02082002B 12.5kg 美国RDI
Methionine/choline deficient diet with 60 kcal% fat A06071301B 12.5kg 美国RDI
choline deficient diet with 0.1% Methionine A06071302 12.5kg 美国RDI
40 kcal% Fat, 20 kcal% Sucrose, and 2% Cholesterol D09100301 12.5kg 美国RDI
 动脉粥样硬化饲料    
动脉粥样硬化是一种复杂的慢性疾病，其特征为脂质在动脉壁堆积，最终形成版块，从而导致动脉缩小、硬化、以及/或者完全阻塞。
 
研究表明，含饱和脂肪和胆固醇的食物与循环胆固醇水平升高密切相关。
 
跟人类一样，西方膳食可诱导某些啮齿类动物（如小鼠、仓鼠和豚鼠）LDL-C升高和动脉粥样硬化。
 
ApoE敲除或者LDL受体敲除小鼠是诱导动脉粥样硬化的易感小鼠。大鼠很难诱导高胆固醇血症，因为当在膳食中添加胆固醇时，大鼠内源性的胆固醇产生迅速下降。然而，通常采用高脂添加胆固醇的饲料（如D12108C和D12079B）来诱导动脉粥样硬化和胆固醇血症，D12079B比D12108C含有更少的胆固醇，发展成动脉粥样硬化比较缓慢。Veillard等对ApoE敲除小鼠喂养D12108C饲料14周，观察到在第8周时，形成相当严重的病变。
 
推荐饲料：D12079B，D12108C。
 推荐产品  货号  规格  生产厂商
High fat rodent diet with 1.25% cholesterol D12108C 12.5kg 美国RDI
5% Sodium Cholic Acid,12.5% Cholesterol D12336 12.5kg 美国RDI
 高血压饲料    
人类高血压的发病机制尚未被完全了解，这种血压持续过高的病症是遗传和环境的多因素共同作用的结果。
 
为了更好的了解其发病机制，促进预防与防治，多种动物模型已经被研发来模仿人类的高血压反应。
 
高血压研究的首选动物模型是的Dahl或SHR大鼠，小鼠并没被广泛使用。
 
高钠饲料通常用于研究膳食诱导高血压，因为增加循环钠水平会使细胞释放水分子，从而提升了对血管壁的压力。
 
推荐饲料：D02011103，D05011703，D10001。
 推荐产品  货号  规格  生产厂商
AIN-76A + 8% Sodium Chloride D05011703 12.5kg 美国RDI
AIN-76A- widely used, balanced,purified rodent diet D10001 12.5kg 美国RDI

金属纳米材料|金属纳米材料|无机试剂|试剂|关东化学株式会社

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超微粒子金属氧化物NanoTek®

平均粒径约30纳米的超微粒子。超微细的粒度，特殊的形状，优秀的流动性和分散性等利用以前的素材，是考虑了各种各样的用途的应用被期待。

稀土超微粒子金属氧化物

平均粒子直径15纳米以下的纳米粒子金属氧化物。超微细粒子直径和稀土金属的特性兼有新材料，各种用途开发被期待。

金属纳米粒子[ Ionic Liquids威盛电子GmbH制]

本公司，德国Ionic Liquids威盛电子GmbH（IoLiTec；总统技术）社的《金属纳米粒子』系列的阵容，希望案内不能接受。总统科技公司，金属单质·金属氧化物·金属碳化物和金属氮化物等各种各样的纳米粒子阵容。另外，包装大小的小容量大容量广泛地准备着。所以，研究开发的检讨阶段·规模合起请使用。

Nano手デライト型（R型）二氧化锰[株式会社前锋科学实验室制]新

并デライト型（R型）的结晶结构具有以下特点二酸化锰拥有，很多功能性产生被知道。 【特点】“质子H +和弱共享结合形成”=“粒子表面上的质子导电能力”，“在水中的质子吸解吸能”； ，敝公司㈱前锋科学实验室（FSL）开发的独自制法（专利第5069881）被制造了的，『Nano手デライト型（R型）二酸化锰》阵容。本系列，高纯度的手デライト型二氧化锰的纳米粒子，下一代电池材料，贵金属回收剂，高度水处理以及水的氧化催化等，用途广泛展开被期待。

金属纳米分散液Metallic Nano Dispersions
[四国测量工业株式会社制]

敝社，微波法被合成了的四国测量工业株式会社制『金属纳米分散液』系列的阵容，希望案内不能接受。该公司的“金属纳米分散液』，微波法的特长的狭窄的粒度分布有金属纳米粒子的分散液。金属小化比表面积变大，散装不同特性和高活性的功能，可以发挥出来，被期待。

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脂肪酸分析用|食品理化学分析|食品分析用试剂|试剂|关东化学株式会社

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脂肪酸构造的差异饱和脂肪酸”和“不饱和脂肪酸”两种被分类。碳-碳间双键的脂肪酸的不饱和脂肪酸和好，变压器型双键拿着的不饱和脂肪酸是变压器脂肪酸和被总称。变压器脂肪酸人造黄油和冰激凌等硬化处理的油脂和它们含食品等含有变压器脂肪酸的摄取血液中的胆固醇的增加，心疾病的风险提高的事被报告。 消费者厅平成23年2月21日，“变压器脂肪酸的情报开示関指针问题”的出现，食品事业者脂肪酸関情报公开实施的时候的想法指明了。今后，食品中含有的脂肪酸的分析法的确立了，必需脂肪酸的标准品也是必不可少的。这一次，我们公司变压器脂肪酸为首的各种各样的脂肪酸标准品各小册子之类中了请介绍一下。

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Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制

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Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制
特克勒德豚鼠饮食是为了满足豚鼠在生命周期的各个阶段的营养需要而制定的完整和平衡的饮食。
植物和鱼粉来源所提供的蛋白质提供了豚鼠所需必需氨基酸的平衡。大豆油中的脂肪提供了良好的毛发所必需的脂肪酸。
特克拉德豚鼠的饮食适当强化维生素和矿物质，以满足豚鼠在生长、维持和繁殖过程中的需要。
维生素C被包括在这些饮食中，因为豚鼠(就像人类和其他灵长类动物一样)需要饮食中的维生素C来防止坏血病。稳定维生素C(L-抗坏血酸-2-聚磷酸)用于延长保质期.
紫花苜蓿粉是一种高品质的饲料产品，有助于维持豚鼠消化系统的正常运转。该公司，颗粒饮食有助于防止饲料浪费。
产品
特克乐豚鼠饲料 不可蒸压式 辐照
全球豚鼠饮食 2040，2040 C 2940
全球高纤维豚鼠饮食 2041 2941
特克乐豚鼠饲料 7006
并不是所有的产品都是在当地库存的，可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时，一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存，可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点，人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲，当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月，有时甚至在生产后12个月。这种实践经验，随着时间的推移，再加上文献支持和维生素测试，让我们相信，这些饮食继续支持动物的健康和研究的完整性，至少在9个月后生产。如果你不确定当地的政策，请向你的机构寻求指导。
建议的储存条件：

  • 凉爽和干燥；在华氏70度或以下，湿度低于50%的理想值，但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中，防止连续暴露于光线下，并将空气暴露在最小范围内。
应该允许几内亚猪[医]锂获得放置在笼的前部或侧面的喂食器中的食物。

Teklad guinea pig diets are complete and balanced diets formulated to meet the nutritional needs of guinea pigs during various stages of the life cycle.
Protein supplied by plant and fish meal sources provides the balance of essential amino acids required by guinea pigs. Fat from soybean oil supplies essential fatty acids necessary for a good hair coat.
Teklad guinea pig diets are properly fortified with vitamins and minerals to meet the needs of guinea pigs during growth, maintenance, and reproduction.
Vitamin C is included in these diets because guinea pigs (as do man and other primates) require a dietary source of vitamin C to prevent scurvy. Stabilized vitamin C (L-ascorbyl-2-polyphosphate) is used to extend the shelf life.
Alfalfa meal is included as a high-quality forage product to help maintain the normal functioning of the guinea pig’s digestive system. The firm, pelleted diet aids in preventing feed wastage.

Products
Teklad guinea pig diets Non-autoclavable form Irradiated
Teklad global guinea pig diet 2040, 2040C 2940
Teklad global high fiber guinea pig diet 2041 2941
Teklad guinea pig diet 7006
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.
COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.
Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air
Guinea pigs should be allowed ad libitum access to diets placed in a feeder attached to the front or side of the cage.

日本 JaICA 老化 Antibody系列产品

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日本 JaICA 老化 Antibody系列产品
上海金畔生物作为日本 JaICA 老化中国代理商，欢迎新老客户访问日本 JaICA 老化官网或者咨询我们获取更多日本 JaICA 老化产品线价格说明书等信息。
日本老化制御研究所 Jaica代理
Anti 8-OHdG/ 8-oxo-dG/ 8-hydroxy-2'-deoxyguanosine monoclonal antibody (N45.1).

8-hydroxy-2′-deoxyguanosine (8-OHdG) is a product of oxidatively damaged DNA formed by hydroxy radical, singlet oxygen and direct photodynamic action. Anti 8-OHdG monoclonal antibody (clone N45.1) is highly specific for 8-OHdG, and is suitable for immunohistochemistry. Cross reactivity have been checked for 8-OHdG analogues (guanosine(G),7-methyl-G, 6-SH-G, 8-Bromo-G, dA, dC, dT, dI, dU, dG, O6-methyl-dG, 8-OHdA, guanine(Gua),O6-methyl-Gua, 8-OH-Gua, uric acid, urea, creatine, creatinine, 8-sulfhydryl-G, 8-OH-G).
Anti thymidine glycol (TG) monoclonal antibody

Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage.
Anti dityrosine (DT) monoclonal antibody (1C3).

Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
Anti dibromotyrosine monoclonal antibody (3A5).

Tyrosine is one of the main targets of protein oxidation, and it have been reported form nitrotyrosine, dityrosine and halogenated tyrosines depending on the type of free radicals. For example, hypochlorous acid (HOCl) and hypobromous acid (HOBr) are derived from neutrophil myeloperoxidase (MPO) and eosinophil peroxidase (EPO), and known to form dihalogenated tyrosines such as DiBrY, DiClY and DiIY. It is expected that DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.
Anti 4-hydroxy-2-nonenal (4-HNE) monoclonal antibody (HNE-J2).

During the peroxidation process, a variery of aldehydes are formed. 4-hydroxy-2-nonenal (4-HNE) is an alpha, beta unsatulated aldehyde that can be formed by peroxidation of omega-6 unsatulated fatty acids such as linoleic acid and arachidonic acid. Especially, 4-HNE formed inside living body is reported to originate from phospholipid-bound arachidonic acid. 4-HNE may be one of the most reliable biomarker of lipid peroxidation. This antibody show almost negligible reactivity with proteins that were treated with other aldehydes, such as 2-nonenal, 2-hexenal, 1-hexanal, 4-hydroxy-2-hexenal,formaldehyde, or glutaraldehyde.
Anti Hexanoyl-Lysine adduct (HEL) monoclonal antibody.

Aldehydes such as malondi-aldehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) have been reported as one of the advanced lipid peroxidation products. But recently in the earlier stage of lipid peroxidation, 13-hydroperoxyoctadecanoic acid (13-HPODE) is found to be covalently bound to proteins1). Hexanoyl-Lysine adduct (HEL) is a novel lipid hydroperoxide-modified lysine residues. HEL is formed by oxidative modification by oxidized omega-6 fatty acids such as linoleic acid or arachidonic acid. This monoclonal antibody is spesific for proteins and peptides containing HEL. Suitable for HEL detection by immunohistochemistry and western blotting.
Anti Acrolein (ACR) monoclonal antibody.

Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. This antibody is specific for the ACR-modified protein, especially FDP-lysine type derivative.
Anti malondialdehyde (MDA) monoclonal antibody.

Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative. This monoclonal antibody is specific for the MDA-modified protein, especially DHP-lysine type derivative.
Anti 4-hydroxy-2-hexenal (4-HHE) monoclonal antibody.

4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enable to detect HHE-His in the tissue samples.
Anti Crotonaldehyde (CRA) monoclonal antibody.

Crotonaldehyde (CRA) is a representative carcinogenic aldehyde formed endogenously through lipid peroxidation. CRA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with CRA and lysine residue leads to the formation of numerous numbers of adducts. This antibody is specific for the CRA-modified protein.
Anti methylglyoxal/ Argpyrimidine (MG) monoclonal antibody.

Methylglyoxal (MG), an endogenous metabolite that increases in diabetes and is a common intermediate in the Maillard reaction (glycation), reacts with proteins and forms advanced glycation end products (AGE). MG reacts with arginine residue in protein and forms numerous numbers of adducts, such as argpyrimidine. This antibody is specific for argpyrimidine: N-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-L-ornithine.
Anti 7-ketocholesterol (7-KC) monoclonal antibody.

Cholesterol oxidation products, especially 7-Ketocholesterol (7KC), have been the focus of much attention because they are present in human atherosclerotic plaque and display a wide range of atherogenic properties in vitro and to some extant in vivo. This antibody is specific for 7KC. This antibody is useful to detect 7KC in tissue samples. A frozen tissue sample is recommended for immunohistochemistry.
Anti nitrotryptophan (NW: 6-NO2-Trp) monoclonal antibody

Reactive nitrogen species (RNS) are formed in a variety of diseases such as atherosclerosis, inflammation, cancer and neurodegenerative disiases. Peroxinitrite (ONOO–) is known as a potent biological oxidant, which is formed via very fast reaction between nitric oxide (NO) and superoxide (O2–). 6-nitrotryptophan (6-NO2-Trp) is shown to be one of the most stable and major ONOO–-modified amino acids, and growing evidences suggest that nitrotryptophan may play a significant role in the cellular regulation under nitrosative stress.

Lumiprobe品牌介绍及代理商 中国授权代理商

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Lumiprobe授权代理商–上海金畔生物

热烈祝贺金畔生物正式成为Lumiprobe中国正规签约授权代理商。
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Lumiprobe Corporation是美国一家高品质生物技术公司，专业提供分子生物学研究用的活性荧光染料。从2006年开始，公司生产并销售生命科学研究和诊断学应用的优质化学药品。产品主要有：活性染料(Reactive Dye)和SYBR Green I 染料，用于寡核苷酸合成的亚磷酰胺，点击化学用染料和其它试剂。 产品主要应用：点击化学(Click Chemistry)、蛋白质组学研究中的双向荧光差异凝胶电泳(2D DIGE)和实时荧光定量PCR(Realtime PCR)。 上海金畔生物科技有限公司作为Lumiprobe中国正规签约授权代理商，上海金畔生物Lumiprobe官网：http://lumiprobe.jinpanbio.com/。可提供Lumiprobe的完整产品线，所有规格产品保证货期5-7工作日到货，满足您的各种科研实验需求。产品包括：羧酸类染料、羰基类染料，标记分子氨基活性染料，标记分子巯基活性染料，动物活体成像用染料，蛋白质、多肽、核酸等生物分子标记染料、点击化学等。渠道正规（市场上部分是分装，质量不能保证），质量保证，价格极具竞争力,而且我们的货期仅需要5-7工作日，不需要像其他家攒单导致货期3-4周。